Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 QL-V-107 2 72
0.01
 18451.0 18525.7 2822.7
-2.0
 0.997 0.996 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17594.0 18525.7 2822.7
-1.5
 0.962 0.950 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17934.0 18525.7 2822.7
-1.5
 0.976 0.968 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17828.0 18525.7 2822.7
-1.5
 0.972 0.962 2.714
HCC1806 QL-V-107 0 2
HCC1806 AZD8055 2 72
0.0316
 15293.0 18525.7 2822.7
-1.5
 0.864 0.826 2.714
HCC1806 AZD8055 0 2
HCC1806 QL-IV-100 2 72
0.001
 18295.0 18525.7 2822.7
-3.0
 0.991 0.988 2.714
HCC1806 QL-IV-100 0 2
HCC1806 QL-V-107 2 72
0.3162
 12296.0 18525.7 2822.7
-0.5
 0.720 0.664 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.3162
 11225.0 18525.7 2822.7
-0.5
 0.663 0.606 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
1.0
 6418.0 18525.7 2822.7
0.0
 0.353 0.346 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
1.0
 6341.0 18525.7 2822.7
0.0
 0.347 0.342 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
3.1623
 1944.0 18525.7 2822.7
0.5
 -0.128 0.105 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
3.1623
 1850.0 18525.7 2822.7
0.5
 -0.144 0.100 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
10.0
 1101.0 18525.7 2822.7
1.0
 -0.293 0.059 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
10.0
 1131.0 18525.7 2822.7
1.0
 -0.286 0.061 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-VIII-58 2 72
0.001
 18626.0 18525.7 2822.7
-3.0
 1.000 1.010 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 QL-VIII-58 2 72
0.001
 17843.0 18525.7 2822.7
-3.0
 0.973 0.963 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 QL-VIII-58 2 72
0.0032
 18970.0 18525.7 2822.7
-2.49
 1.020 1.020 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 QL-VIII-58 2 72
0.0032
 18932.0 18525.7 2822.7
-2.49
 1.020 1.020 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 QL-VIII-58 2 72
0.01
 18323.0 18525.7 2822.7
-2.0
 0.992 0.989 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 QL-VIII-58 2 72
0.01
 18375.0 18525.7 2822.7
-2.0
 0.994 0.992 2.714
HCC1806 QL-VIII-58 0 2
HCC1806 AZD8055 2 72
0.001
 18239.0 18525.7 2822.7
-3.0
 0.989 0.985 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 11898.0 18525.7 2822.7
-2.49
 0.699 0.642 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.001
 18210.0 18525.7 2822.7
-3.0
 0.987 0.983 2.714
HCC1806 AZD8055 0 2
HCC1806 QL-XII-47 2 72
0.3162
 16886.0 18525.7 2822.7
-0.5
 0.933 0.911 2.714
HCC1806 QL-XII-47 0 2
HCC1806 QL-XII-47 2 72
0.3162
 17488.0 18525.7 2822.7
-0.5
 0.958 0.944 2.714
HCC1806 QL-XII-47 0 2