Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset - HMS LINCS Database

Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line	Drug name	Experimental replicate	Timepoint	Drug concentration	Live cell count	Average live cell count, DMSO control	Average live cell count (time = 0)	Log10(drug concentration)	GR value	Relative cell count (treatment versus DMSO)	Cell doublings (DMSO control)	Experiment name
HCC1806	AZD8055	2	72	0.0316	15293.0	18525.7	2822.7	-1.5	0.864	0.826	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.3162	8751.0	18525.7	2822.7	-0.5	0.517	0.472	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0032	18039.0	18525.7	2822.7	-2.49	0.980	0.974	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0316	15618.0	18525.7	2822.7	-1.5	0.878	0.843	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.1	12537.0	18525.7	2822.7	-1.0	0.732	0.677	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.3162	9550.0	18525.7	2822.7	-0.5	0.567	0.516	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.001	17923.0	18525.7	2822.7	-3.0	0.976	0.967	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0032	11898.0	18525.7	2822.7	-2.49	0.699	0.642	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.01	17722.0	18525.7	2822.7	-2.0	0.968	0.957	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0316	15946.0	18525.7	2822.7	-1.5	0.893	0.861	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.1	12142.0	18525.7	2822.7	-1.0	0.712	0.655	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.1	12244.0	18525.7	2822.7	-1.0	0.717	0.661	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.1	11490.0	18525.7	2822.7	-1.0	0.677	0.620	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.3162	9698.0	18525.7	2822.7	-0.5	0.576	0.523	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.001	18210.0	18525.7	2822.7	-3.0	0.987	0.983	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.001	18239.0	18525.7	2822.7	-3.0	0.989	0.985	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.001	18510.0	18525.7	2822.7	-3.0	0.999	0.999	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0032	18499.0	18525.7	2822.7	-2.49	0.999	0.999	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0032	18863.0	18525.7	2822.7	-2.49	1.010	1.020	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.01	17226.0	18525.7	2822.7	-2.0	0.947	0.930	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.01	18160.0	18525.7	2822.7	-2.0	0.985	0.980	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.01	16856.0	18525.7	2822.7	-2.0	0.932	0.910	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.0316	15357.0	18525.7	2822.7	-1.5	0.866	0.829	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	1.0	8645.0	18525.7	2822.7	0.0	0.510	0.467	2.714	HCC1806 AZD8055 0 2
HCC1806	AZD8055	2	72	0.3162	9071.0	18525.7	2822.7	-0.5	0.537	0.490	2.714	HCC1806 AZD8055 0 2

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HMS LINCS Project

Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)