Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 6598.0 | 18525.7 | 2822.7 | 0.5 | 0.367 | 0.356 | 2.714 | HCC1806 Torin1 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 59.0 | 7167.9 | 2409.0 | 0.5 | -0.905 | 0.008 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 43.0 | 7167.9 | 2409.0 | 0.5 | -0.923 | 0.006 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 48.0 | 7167.9 | 2409.0 | 0.5 | -0.917 | 0.007 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 2031.0 | 7580.8 | 2503.8 | 0.5 | -0.123 | 0.268 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 96.0 | 6533.6 | 1943.1 | 0.5 | -0.821 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 561.0 | 7580.8 | 2503.8 | 0.5 | -0.608 | 0.074 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2838.0 | 7167.9 | 2409.0 | 0.5 | 0.110 | 0.396 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 3.1623 | 6040.0 | 7167.9 | 2409.0 | 0.5 | 0.794 | 0.843 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-V-107 | 3 | 72 | 3.1623 | 648.0 | 6533.6 | 1943.1 | 0.5 | -0.466 | 0.099 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | Torin2 | 2 | 72 | 3.1623 | 17.0 | 7167.9 | 2409.0 | 0.5 | -0.957 | 0.002 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2831.0 | 7167.9 | 2409.0 | 0.5 | 0.108 | 0.395 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 788.0 | 7167.9 | 2409.0 | 0.5 | -0.509 | 0.110 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3277.0 | 6533.6 | 1943.1 | 0.5 | 0.348 | 0.502 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 1816.0 | 7580.8 | 2503.8 | 0.5 | -0.182 | 0.240 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2848.0 | 7167.9 | 2409.0 | 0.5 | 0.112 | 0.397 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3490.0 | 6533.6 | 1943.1 | 0.5 | 0.398 | 0.534 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 870.0 | 7167.9 | 2409.0 | 0.5 | -0.477 | 0.121 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3495.0 | 6533.6 | 1943.1 | 0.5 | 0.399 | 0.535 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2590.0 | 7167.9 | 2409.0 | 0.5 | 0.047 | 0.361 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 642.0 | 7580.8 | 2503.8 | 0.5 | -0.573 | 0.085 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1239.0 | 17793.8 | 2895.7 | 0.5 | -0.277 | 0.070 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 3.1623 | 1180.0 | 17793.8 | 2895.7 | 0.5 | -0.290 | 0.066 | 2.619 | HCC1806 Torin2 0 1 |