Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 459.0 | 7167.9 | 2409.0 | 0.5 | -0.651 | 0.064 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 544.0 | 6533.6 | 1943.1 | 0.5 | -0.517 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 686.0 | 7580.8 | 2503.8 | 0.5 | -0.555 | 0.091 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 518.0 | 7167.9 | 2409.0 | 0.5 | -0.624 | 0.072 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 540.0 | 6533.6 | 1943.1 | 0.5 | -0.519 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 536.0 | 6533.6 | 1943.1 | 0.5 | -0.521 | 0.082 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2571.0 | 6533.6 | 1943.1 | 0.5 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 529.0 | 7580.8 | 2503.8 | 0.5 | -0.622 | 0.070 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 566.0 | 7167.9 | 2409.0 | 0.5 | -0.602 | 0.079 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2590.0 | 7167.9 | 2409.0 | 0.5 | 0.047 | 0.361 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 3.1623 | 585.0 | 7167.9 | 2409.0 | 0.5 | -0.593 | 0.082 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2477.0 | 6533.6 | 1943.1 | 0.5 | 0.149 | 0.379 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3326.0 | 7580.8 | 2503.8 | 0.5 | 0.194 | 0.439 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2446.0 | 6533.6 | 1943.1 | 0.5 | 0.141 | 0.374 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2838.0 | 7167.9 | 2409.0 | 0.5 | 0.110 | 0.396 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3106.0 | 7580.8 | 2503.8 | 0.5 | 0.144 | 0.410 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 642.0 | 7580.8 | 2503.8 | 0.5 | -0.573 | 0.085 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 561.0 | 7580.8 | 2503.8 | 0.5 | -0.608 | 0.074 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3152.0 | 7580.8 | 2503.8 | 0.5 | 0.155 | 0.416 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2831.0 | 7167.9 | 2409.0 | 0.5 | 0.108 | 0.395 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2848.0 | 7167.9 | 2409.0 | 0.5 | 0.112 | 0.397 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2404.0 | 6533.6 | 1943.1 | 0.5 | 0.129 | 0.368 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 3.1623 | 753.0 | 7580.8 | 2503.8 | 0.5 | -0.528 | 0.099 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 582.0 | 6533.6 | 1943.1 | 0.5 | -0.498 | 0.089 | 1.750 | HCC70 QL-IV-100 0 3 |