Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18863.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.020 | 2.714 | HCC1806 AZD8055 0 2 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.01 | 18851.0 | 18525.7 | 2822.7 | -2.0 | 1.010 | 1.020 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 18841.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0032 | 18790.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 18790.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0316 | 18768.0 | 18525.7 | 2822.7 | -1.5 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-X-138 | 2 | 72 | 0.1 | 18763.0 | 18525.7 | 2822.7 | -1.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 18752.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.001 | 18744.0 | 18525.7 | 2822.7 | -3.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 18742.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.010 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0316 | 18736.0 | 18525.7 | 2822.7 | -1.5 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.01 | 18730.0 | 17793.8 | 2895.7 | -2.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.001 | 18727.0 | 17793.8 | 2895.7 | -3.0 | 1.040 | 1.050 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.01 | 18705.0 | 18525.7 | 2822.7 | -2.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 18684.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.1 | 18676.0 | 18525.7 | 2822.7 | -1.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.0316 | 18674.0 | 17793.8 | 2895.7 | -1.5 | 1.040 | 1.050 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 18659.0 | 17793.8 | 2895.7 | -1.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.1 | 18647.0 | 17793.8 | 2895.7 | -1.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 18646.0 | 18525.7 | 2822.7 | -2.0 | 1.000 | 1.010 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 18631.0 | 17793.8 | 2895.7 | -3.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.0316 | 18630.0 | 17793.8 | 2895.7 | -1.5 | 1.040 | 1.050 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.001 | 18626.0 | 18525.7 | 2822.7 | -3.0 | 1.000 | 1.010 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 18605.0 | 17793.8 | 2895.7 | -2.49 | 1.030 | 1.050 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 18598.0 | 18525.7 | 2822.7 | -2.49 | 1.000 | 1.000 | 2.714 | HCC1806 QL-IV-100 0 2 |