Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-V-73 | 2 | 72 | 0.0316 | 17692.0 | 18525.7 | 2822.7 | -1.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0316 | 17687.0 | 18525.7 | 2822.7 | -1.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-V-73 | 2 | 72 | 0.3162 | 17685.0 | 18525.7 | 2822.7 | -0.5 | 0.966 | 0.955 | 2.714 | HCC1806 QL-V-73 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.3162 | 17680.0 | 18525.7 | 2822.7 | -0.5 | 0.966 | 0.954 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 0.01 | 17680.0 | 18525.7 | 2822.7 | -2.0 | 0.966 | 0.954 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 0.001 | 17677.0 | 18525.7 | 2822.7 | -3.0 | 0.966 | 0.954 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.001 | 17670.0 | 17793.8 | 2895.7 | -3.0 | 0.995 | 0.993 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17665.0 | 18525.7 | 2822.7 | -0.5 | 0.965 | 0.954 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.3162 | 17662.0 | 17793.8 | 2895.7 | -0.5 | 0.994 | 0.993 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 17648.0 | 17793.8 | 2895.7 | -3.0 | 0.994 | 0.992 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-X-138 | 2 | 72 | 0.0316 | 17632.0 | 18525.7 | 2822.7 | -1.5 | 0.964 | 0.952 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.3162 | 17624.0 | 17793.8 | 2895.7 | -0.5 | 0.993 | 0.990 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.001 | 17620.0 | 18525.7 | 2822.7 | -3.0 | 0.963 | 0.951 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-X-138 | 1 | 72 | 0.3162 | 17618.0 | 17793.8 | 2895.7 | -0.5 | 0.992 | 0.990 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 17610.0 | 17793.8 | 2895.7 | -3.0 | 0.992 | 0.990 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17595.0 | 18525.7 | 2822.7 | -0.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17594.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 0.0032 | 17594.0 | 18525.7 | 2822.7 | -2.49 | 0.962 | 0.950 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0316 | 17591.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 17589.0 | 17793.8 | 2895.7 | 0.0 | 0.991 | 0.988 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.3162 | 17588.0 | 17793.8 | 2895.7 | -0.5 | 0.991 | 0.988 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 17584.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.949 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-VI-86 | 1 | 72 | 0.0316 | 17581.0 | 17793.8 | 2895.7 | -1.5 | 0.991 | 0.988 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17579.0 | 18525.7 | 2822.7 | -0.5 | 0.962 | 0.949 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | Torin1 | 1 | 72 | 0.0032 | 17574.0 | 17793.8 | 2895.7 | -2.49 | 0.991 | 0.988 | 2.619 | HCC1806 Torin1 0 1 |