Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-47 | 2 | 72 | 0.1 | 16238.0 | 18525.7 | 2822.7 | -1.0 | 0.905 | 0.877 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.1 | 19394.0 | 18525.7 | 2822.7 | -1.0 | 1.030 | 1.050 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.1 | 18676.0 | 18525.7 | 2822.7 | -1.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.3162 | 17680.0 | 18525.7 | 2822.7 | -0.5 | 0.966 | 0.954 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.3162 | 17488.0 | 18525.7 | 2822.7 | -0.5 | 0.958 | 0.944 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.3162 | 16886.0 | 18525.7 | 2822.7 | -0.5 | 0.933 | 0.911 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.3162 | 18252.0 | 18525.7 | 2822.7 | -0.5 | 0.989 | 0.985 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 1.0 | 3780.0 | 18525.7 | 2822.7 | 0.0 | 0.114 | 0.204 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 1.0 | 8371.0 | 18525.7 | 2822.7 | 0.0 | 0.493 | 0.452 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 1.0 | 6630.0 | 18525.7 | 2822.7 | 0.0 | 0.370 | 0.358 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 1.0 | 8795.0 | 18525.7 | 2822.7 | 0.0 | 0.520 | 0.475 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1099.0 | 18525.7 | 2822.7 | 0.5 | -0.294 | 0.059 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 996.0 | 18525.7 | 2822.7 | 0.5 | -0.319 | 0.054 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 967.0 | 18525.7 | 2822.7 | 0.5 | -0.326 | 0.052 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 3.1623 | 1062.0 | 18525.7 | 2822.7 | 0.5 | -0.302 | 0.057 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 363.0 | 18525.7 | 2822.7 | 1.0 | -0.530 | 0.020 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 348.0 | 18525.7 | 2822.7 | 1.0 | -0.538 | 0.019 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 258.0 | 18525.7 | 2822.7 | 1.0 | -0.586 | 0.014 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 10.0 | 340.0 | 18525.7 | 2822.7 | 1.0 | -0.541 | 0.018 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.001 | 14643.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.001 | 13884.0 | 14413.7 | 2222.1 | -3.0 | 0.972 | 0.963 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.001 | 14313.0 | 14413.7 | 2222.1 | -3.0 | 0.995 | 0.993 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.001 | 14082.0 | 14413.7 | 2222.1 | -3.0 | 0.983 | 0.977 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.0032 | 14718.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 0.0032 | 16020.0 | 14413.7 | 2222.1 | -2.49 | 1.080 | 1.110 | 2.697 | HCC1806 QL-XII-47 0 3 |