Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 1 | 72 | 0.01 | 18200.0 | 17793.8 | 2895.7 | -2.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.0316 | 17096.0 | 17793.8 | 2895.7 | -1.5 | 0.970 | 0.961 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.0316 | 17320.0 | 17793.8 | 2895.7 | -1.5 | 0.980 | 0.973 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.0316 | 18334.0 | 17793.8 | 2895.7 | -1.5 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.0316 | 18129.0 | 17793.8 | 2895.7 | -1.5 | 1.010 | 1.020 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 18264.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 17975.0 | 17793.8 | 2895.7 | -1.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 18659.0 | 17793.8 | 2895.7 | -1.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.1 | 18461.0 | 17793.8 | 2895.7 | -1.0 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.3162 | 18405.0 | 17793.8 | 2895.7 | -0.5 | 1.030 | 1.030 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.3162 | 17387.0 | 17793.8 | 2895.7 | -0.5 | 0.982 | 0.977 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.3162 | 17624.0 | 17793.8 | 2895.7 | -0.5 | 0.993 | 0.990 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 0.3162 | 16681.0 | 17793.8 | 2895.7 | -0.5 | 0.951 | 0.937 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 15572.0 | 17793.8 | 2895.7 | 0.0 | 0.901 | 0.875 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 15014.0 | 17793.8 | 2895.7 | 0.0 | 0.874 | 0.844 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 16603.0 | 17793.8 | 2895.7 | 0.0 | 0.948 | 0.933 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 15881.0 | 17793.8 | 2895.7 | 0.0 | 0.915 | 0.893 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 13109.0 | 17793.8 | 2895.7 | 0.5 | 0.780 | 0.737 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 12305.0 | 17793.8 | 2895.7 | 0.5 | 0.737 | 0.692 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 12330.0 | 17793.8 | 2895.7 | 0.5 | 0.739 | 0.693 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 3.1623 | 12866.0 | 17793.8 | 2895.7 | 0.5 | 0.767 | 0.723 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 10.0 | 6488.0 | 17793.8 | 2895.7 | 1.0 | 0.361 | 0.365 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 10.0 | 6893.0 | 17793.8 | 2895.7 | 1.0 | 0.393 | 0.387 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 10.0 | 6533.0 | 17793.8 | 2895.7 | 1.0 | 0.364 | 0.367 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC1806 | QL-XII-108 | 1 | 72 | 10.0 | 6690.0 | 17793.8 | 2895.7 | 1.0 | 0.377 | 0.376 | 2.619 | HCC1806 QL-XII-108 0 1 |