Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 AZD8055 1 72
3.1623
 8321.0 17793.8 2895.7
0.5
 0.496 0.468 2.619
HCC1806 AZD8055 0 1
HCC1806 AZD8055 1 72
3.1623
 7396.0 17793.8 2895.7
0.5
 0.430 0.416 2.619
HCC1806 AZD8055 0 1
HCC1806 AZD8055 1 72
10.0
 6394.0 17793.8 2895.7
1.0
 0.353 0.359 2.619
HCC1806 AZD8055 0 1
HCC1806 AZD8055 1 72
10.0
 6761.0 17793.8 2895.7
1.0
 0.382 0.380 2.619
HCC1806 AZD8055 0 1
HCC1806 AZD8055 1 72
10.0
 7210.0 17793.8 2895.7
1.0
 0.417 0.405 2.619
HCC1806 AZD8055 0 1
HCC1806 AZD8055 2 72
0.001
 18210.0 18525.7 2822.7
-3.0
 0.987 0.983 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.001
 18239.0 18525.7 2822.7
-3.0
 0.989 0.985 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.001
 17923.0 18525.7 2822.7
-3.0
 0.976 0.967 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.001
 18510.0 18525.7 2822.7
-3.0
 0.999 0.999 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 18499.0 18525.7 2822.7
-2.49
 0.999 0.999 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 11898.0 18525.7 2822.7
-2.49
 0.699 0.642 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 18039.0 18525.7 2822.7
-2.49
 0.980 0.974 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0032
 18863.0 18525.7 2822.7
-2.49
 1.010 1.020 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 17226.0 18525.7 2822.7
-2.0
 0.947 0.930 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 17722.0 18525.7 2822.7
-2.0
 0.968 0.957 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 18160.0 18525.7 2822.7
-2.0
 0.985 0.980 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.01
 16856.0 18525.7 2822.7
-2.0
 0.932 0.910 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15946.0 18525.7 2822.7
-1.5
 0.893 0.861 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15618.0 18525.7 2822.7
-1.5
 0.878 0.843 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15293.0 18525.7 2822.7
-1.5
 0.864 0.826 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.0316
 15357.0 18525.7 2822.7
-1.5
 0.866 0.829 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 12142.0 18525.7 2822.7
-1.0
 0.712 0.655 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 12244.0 18525.7 2822.7
-1.0
 0.717 0.661 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 12537.0 18525.7 2822.7
-1.0
 0.732 0.677 2.714
HCC1806 AZD8055 0 2
HCC1806 AZD8055 2 72
0.1
 11490.0 18525.7 2822.7
-1.0
 0.677 0.620 2.714
HCC1806 AZD8055 0 2