Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset - HMS LINCS Database

Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset (ID:20365)

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

|<
<<
Previous
Page 10 of 18
Next
>>
>
226 to 250 of 432 records
per page:

Cell line	Drug name	Experimental replicate	Timepoint	Curve type (GR values)	Curve type (relative cell counts)	Experiment name	Number of concentrations	Cell doublings (DMSO control)	GR50	GRmax	GR_AOC	GEC50	GRinf	Hill slope (GR values)	R-squared sigmoid fit (GR values)	P-value sigmoid fit (GR values)	R-squared flat fit (GR values)	IC50	Emax	AUC	EC50	Einf	Hill slope (relative cell counts)	R-squared sigmoid fit (relative cell counts)	P-value sigmoid fit (relative cell counts)	R-squared flat fit (relative cell counts)
BT-549	Omipalisib	3	72	sigmoid	sigmoid	BT549 omipalisib 0 3 72	8	1.777	0.0114	-0.23	0.753	0.0162	-0.178	0.879	0.988	1.64e-06	NA	0.0201	0.183	0.459	0.0112	0.208	0.924	0.991	6.53e-07	NA
BT-549	Omipalisib	2	72	sigmoid	sigmoid	BT549 omipalisib 0 2 72	8	1.990	0.0104	-0.291	0.751	0.026	-0.32	0.542	0.966	4.09e-05	NA	0.0175	0.127	0.422	0.011	0.118	0.58	0.953	0.000102	NA
BT-549	Omipalisib	1	72	sigmoid	sigmoid	BT549 omipalisib 0 1 72	8	1.789	0.0164	-0.2	0.693	0.0219	-0.149	0.887	0.986	2.66e-06	NA	0.0272	0.194	0.495	0.0148	0.228	0.993	0.991	8.42e-07	NA
HCC38	Omipalisib	3	72	sigmoid	sigmoid	HCC38 omipalisib 0 3 72	8	1.446	0.0145	-0.503	0.802	0.0539	-0.597	0.6	0.993	3.08e-07	NA	0.0449	0.134	0.499	0.0308	0.107	0.644	0.993	2.98e-07	NA
HCC38	Omipalisib	2	72	sigmoid	sigmoid	HCC38 omipalisib 0 2 72	8	2.124	0.0404	-0.47	0.634	0.45	-1.0	0.456	0.979	9.71e-06	NA	0.0507	0.0595	0.494	0.0507	0.0	0.556	0.96	6.44e-05	NA
HCC38	Omipalisib	1	72	sigmoid	sigmoid	HCC38 omipalisib 0 1 72	8	1.760	0.0231	-0.316	0.672	0.152	-0.638	0.438	0.97	2.61e-05	NA	0.0585	0.151	0.512	0.0499	0.0356	0.465	0.956	8.65e-05	NA
HCC1806	Omipalisib	3	72	sigmoid	sigmoid	HCC1806 omipalisib 0 3 72	8	3.217	0.147	-0.221	0.437	0.71	-0.707	0.559	0.981	7.41e-06	NA	0.0642	0.0481	0.54	0.0538	0.0749	0.919	0.979	9.93e-06	NA
BT-20	Omipalisib	1	72	sigmoid	sigmoid	BT20 omipalisib 0 1 72	8	2.078	0.00617	-0.729	0.985	0.0283	-0.739	0.596	0.97	2.83e-05	NA	0.00781	0.0157	0.306	0.00685	0.0597	0.96	0.988	1.57e-06	NA
BT-20	Omipalisib	3	72	sigmoid	sigmoid	BT20 omipalisib 0 3 72	8	2.586	0.00689	-0.587	0.893	0.044	-0.714	0.478	0.958	7.32e-05	NA	0.00572	0.017	0.281	0.00491	0.0669	0.945	0.983	4.7e-06	NA
HCC1806	PI103	2	72	sigmoid	sigmoid	HCC1806 PI-103 0 2 72	8	2.758	Inf	0.898	0.00662	1.71	0.857	1.43	0.781	0.0105	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA
Hs 578T	PI103	3		sigmoid	sigmoid	Hs578T PI-103 3	8	2.807	0.321	0.175	0.26	0.231	0.163	1.21	0.991	8.05e-07	NA	0.232	0.225	0.729	0.145	0.239	1.39	0.986	2.82e-06	NA
Hs 578T	PI103	2		sigmoid	sigmoid	Hs578T PI-103 2	8	2.503	0.223	-0.0213	0.356	0.303	-0.15	0.858	0.999	7.33e-10	NA	0.206	0.167	0.661	0.152	0.121	0.921	0.999	1.9e-09	NA
Hs 578T	PI103	1		sigmoid	sigmoid	Hs578T PI-103 1	8	2.062	0.131	-0.0743	0.433	0.182	-0.173	0.898	0.996	4.43e-08	NA	0.175	0.204	0.643	0.117	0.152	0.898	0.995	1.02e-07	NA
HCC38	PI103	3	72	sigmoid	sigmoid	HCC38 PI-103 0 3 72	8	1.481	1.26	0.114	0.168	3.16	-0.762	1.01	0.986	2.53e-06	NA	2.34	0.42	0.884	2.34	0.0	1.03	0.983	4.94e-06	NA
HCC38	PI103	2	72	sigmoid	sigmoid	HCC38 PI-103 0 2 72	8	2.094	0.856	0.226	0.167	0.672	0.135	1.3	0.986	2.7e-06	NA	1.04	0.359	0.851	0.488	0.33	1.43	0.981	6.52e-06	NA
HCC38	PI103	1	72	sigmoid	sigmoid	HCC38 PI-103 0 1 72	8	1.782	0.755	0.222	0.201	0.601	0.12	1.2	0.996	4.45e-08	NA	1.39	0.416	0.839	0.494	0.359	1.23	0.995	1.01e-07	NA
BT-20	PI103	1	72	sigmoid	sigmoid	BT20 PI-103 0 1 72	8	1.924	0.646	-0.0114	0.16	0.659	-0.0268	2.6	0.978	1.1e-05	NA	0.753	0.258	0.883	0.579	0.252	2.68	0.964	4.79e-05	NA
BT-20	PI103	2	72	sigmoid	sigmoid	BT20 PI-103 0 2 72	8	1.725	0.235	-0.21	0.388	0.289	-0.212	1.7	0.975	1.64e-05	NA	0.319	0.202	0.721	0.239	0.205	1.81	0.961	5.88e-05	NA
BT-20	PI103	3	72	sigmoid	sigmoid	BT20 PI-103 0 3 72	8	2.496	0.373	0.0139	0.282	0.387	-0.0286	1.52	0.994	1.99e-07	NA	0.359	0.183	0.735	0.279	0.162	1.56	0.988	1.71e-06	NA
HCC1806	PI103	3	72	sigmoid	sigmoid	HCC1806 PI-103 0 3 72	8	3.126	Inf	0.91	0.00588	1.72	0.873	1.43	0.782	0.0103	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA
BT-549	PI103	3	72	sigmoid	sigmoid	BT549 PI-103 0 3 72	8	1.758	0.16	0.00249	0.391	0.166	-0.0225	1.12	0.989	1.19e-06	NA	0.279	0.297	0.704	0.134	0.28	1.12	0.985	3.23e-06	NA
HCC70	PI103	1	72	sigmoid	sigmoid	HCC70 PI-103 0 1 72	8	1.305	1.04	-0.0102	0.104	1.14	-0.107	2.26	0.957	7.9e-05	NA	1.83	0.399	0.938	1.08	0.349	2.28	0.949	0.000133	NA
HCC70	PI103	2	72	sigmoid	sigmoid	HCC70 PI-103 0 2 72	8	1.739	1.19	0.0238	0.151	2.67	-0.766	1.15	0.997	2.59e-08	NA	1.68	0.312	0.885	1.68	0.0	1.21	0.996	6.86e-08	NA
HCC70	PI103	3	72	sigmoid	sigmoid	HCC70 PI-103 0 3 72	8	2.446	1.51	0.227	0.0983	1.57	-0.0288	1.54	0.986	2.66e-06	NA	1.48	0.303	0.906	1.15	0.168	1.59	0.976	1.42e-05	NA
HCC1806	PI103	1	72	sigmoid	sigmoid	HCC1806 PI-103 0 1 72	8	2.673	Inf	0.895	0.00682	1.71	0.853	1.43	0.781	0.0106	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA

|<
<<
Previous
Page 10 of 18
Next
>>
>
226 to 250 of 432 records
per page:

HMS LINCS Project

Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset (ID:20365)