Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset - HMS LINCS Database

Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset (ID:20365)

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

|<
<<
Previous
Page 3 of 18
Next
>>
>
51 to 75 of 432 records
per page:

Cell line	Drug name	Experimental replicate	Timepoint	Curve type (GR values)	Curve type (relative cell counts)	Experiment name	Number of concentrations	Cell doublings (DMSO control)	GR50	GRmax	GR_AOC	GEC50	GRinf	Hill slope (GR values)	R-squared sigmoid fit (GR values)	P-value sigmoid fit (GR values)	R-squared flat fit (GR values)	IC50	Emax	AUC	EC50	Einf	Hill slope (relative cell counts)	R-squared sigmoid fit (relative cell counts)	P-value sigmoid fit (relative cell counts)	R-squared flat fit (relative cell counts)
HCC1806	PIK-93	1	72	sigmoid	sigmoid	HCC1806 PIK-93 0 1 72	8	2.753	44.0	0.853	0.0391	304.0	-1.0	0.568	0.858	0.00285	NA	46.6	0.811	0.948	46.6	0.0	0.57	0.84	0.00406	NA
HCC1806	PIK-93	2	72	sigmoid	sigmoid	HCC1806 PIK-93 0 2 72	8	2.838	41.1	0.857	0.038	265.0	-1.0	0.59	0.858	0.00286	NA	46.6	0.811	0.948	46.6	0.0	0.57	0.84	0.00406	NA
Hs 578T	KIN001-244	3		sigmoid	sigmoid	Hs578T KIN001-244 3	8	2.888	Inf	0.866	0.00909	5.05	0.617	1.35	0.858	0.00289	NA	50.0	0.818	0.988	5.2	0.474	1.31	0.842	0.00391	NA
HCC38	MK2206	3	72	sigmoid	sigmoid	HCC38 MK-2206 0 3 72	8	1.445	71.7	0.728	0.123	320.0	-0.26	0.28	0.854	0.0031	NA	Inf	0.81	0.912	4.3	0.61	0.332	0.834	0.00461	NA
BT-549	KIN001-244	1	72	sigmoid	sigmoid	BT549 KIN001-244 0 1 72	8	1.802	Inf	0.872	0.0273	4.85	0.695	0.794	0.852	0.00324	NA	Inf	0.888	0.976	4.84	0.733	0.786	0.846	0.00362	NA
HCC70	PIK-93	3	72	sigmoid	sigmoid	HCC70 PIK-93 0 3 72	8	2.519	21.2	0.756	0.0663	181.0	-1.0	0.513	0.851	0.00333	NA	34.1	0.721	0.92	34.1	0.0	0.473	0.831	0.00487	NA
HCC38	AZD-6482	3	72	sigmoid	sigmoid	HCC38 AZD6482 0 3 72	8	1.420	Inf	0.821	0.0615	0.324	0.826	5.0	0.849	0.00342	NA	Inf	0.875	0.957	0.323	0.879	5.0	0.846	0.00367	NA
BT-20	AS605240	2	72	sigmoid	sigmoid	BT20 AS-605240 0 2 72	8	1.846	4509270.0	0.729	0.203	320.0	0.31	0.101	0.845	0.00373	NA	4.4e+12	0.764	0.821	56.5	0.46	0.101	0.843	0.00388	NA
BT-20	Alpelisib	2	72	sigmoid	sigmoid	BT20 alpelisib 0 2 72	8	1.692	0.253	-0.0994	0.405	2.25	-1.0	0.503	0.835	0.00451	NA	0.612	0.259	0.698	0.612	0.0	0.507	0.764	0.0131	NA
HCC38	AZD-6482	2	72	sigmoid	sigmoid	HCC38 AZD6482 0 2 72	8	2.132	Inf	0.898	0.0351	4.71	0.773	0.497	0.824	0.0055	NA	Inf	0.894	0.963	4.7	0.765	0.492	0.82	0.00588	NA
BT-549	MK2206	2	72	sigmoid	sigmoid	BT549 MK-2206 0 2 72	8	1.871	Inf	0.926	0.0188	0.107	0.926	5.0	0.816	0.00627	NA	Inf	0.932	0.983	0.107	0.931	5.0	0.809	0.00694	NA
HCC38	XL147	3	72	sigmoid	sigmoid	HCC38 pilaralisib 0 3 72	8	1.420	Inf	0.909	0.0219	0.114	0.921	5.0	0.815	0.00631	NA	Inf	0.936	0.985	0.114	0.945	5.0	0.813	0.00654	NA
HCC1806	Pictilisib	3	72	sigmoid	sigmoid	HCC1806 pictilisib 0 3 72	8	3.234	14.1	0.818	0.0423	52.2	-0.98	0.831	0.814	0.00649	NA	11.3	0.734	0.935	11.3	0.0	0.849	0.773	0.0116	NA
HCC1806	Pictilisib	2	72	sigmoid	sigmoid	HCC1806 pictilisib 0 2 72	8	2.866	12.1	0.796	0.0476	45.4	-1.0	0.831	0.811	0.00671	NA	11.3	0.734	0.935	11.3	0.0	0.849	0.773	0.0116	NA
HCC1806	Pictilisib	1	72	sigmoid	sigmoid	HCC1806 pictilisib 0 1 72	8	2.782	11.7	0.79	0.049	43.7	-1.0	0.831	0.811	0.00677	NA	11.3	0.734	0.935	11.3	0.0	0.849	0.773	0.0116	NA
BT-20	PIK-93	2	72	sigmoid	sigmoid	BT20 PIK-93 0 2 72	8	1.798	0.792	0.155	0.286	14.1	-1.0	0.382	0.81	0.00687	NA	2.8	0.373	0.764	2.8	0.0	0.344	0.77	0.0121	NA
BT-20	Omipalisib	2	72	sigmoid	sigmoid	BT20 omipalisib 0 2 72	8	1.717	0.00324	-0.799	1.1	0.00361	-0.354	4.99	0.808	0.00704	NA	0.00518	0.0194	0.291	0.00429	0.111	1.34	0.968	3.16e-05	NA
BT-20	Pictilisib	2	72	sigmoid	sigmoid	BT20 pictilisib 0 2 72	8	1.746	0.308	-0.0521	0.379	2.35	-1.0	0.54	0.791	0.00908	NA	0.634	0.272	0.712	0.634	0.0	0.6	0.716	0.0229	NA
Hs 578T	Everolimus	2		sigmoid	sigmoid	Hs578T everolimus 2	8	2.550	3210000000.0	0.626	0.335	0.000205	0.476	0.1	0.791	0.00913	NA	18938.0	0.59	0.627	0.000153	0.422	0.1	0.745	0.0166	NA
HCC1806	PI103	3	72	sigmoid	sigmoid	HCC1806 PI-103 0 3 72	8	3.126	Inf	0.91	0.00588	1.72	0.873	1.43	0.782	0.0103	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA
HCC1806	PI103	2	72	sigmoid	sigmoid	HCC1806 PI-103 0 2 72	8	2.758	Inf	0.898	0.00662	1.71	0.857	1.43	0.781	0.0105	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA
HCC70	Alpelisib	1	72	sigmoid	sigmoid	HCC70 alpelisib 0 1 72	8	1.383	4.4	0.574	0.105	20.4	-1.0	0.717	0.78	0.0106	NA	11.9	0.718	0.929	11.9	0.0	0.732	0.768	0.0124	NA
HCC1806	PI103	1	72	sigmoid	sigmoid	HCC1806 PI-103 0 1 72	8	2.673	Inf	0.895	0.00682	1.71	0.853	1.43	0.781	0.0106	NA	Inf	0.866	0.992	1.61	0.817	1.44	0.762	0.0134	NA
HCC70	PIK-93	1	72	sigmoid	sigmoid	HCC70 PIK-93 0 1 72	8	1.442	3.47	0.482	0.137	18.6	-1.0	0.656	0.774	0.0116	NA	10.7	0.649	0.904	10.7	0.0	0.632	0.746	0.0163	NA
HCC38	CAL-101	1	72	sigmoid	sigmoid	HCC38 idelalisib 0 1 72	8	1.723	Inf	0.92	0.00328	1.18	0.903	1.47	0.768	0.0125	NA	Inf	0.932	0.997	1.16	0.918	1.48	0.763	0.0133	NA

|<
<<
Previous
Page 3 of 18
Next
>>
>
51 to 75 of 432 records
per page:

HMS LINCS Project

Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset (ID:20365)