Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 2 of 2: GR metrics. - Dataset (ID:20365)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Curve type (GR values) Curve type (relative cell counts) Experiment name Number of concentrations Cell doublings (DMSO control) GR50 GRmax GR_AOC GEC50 GRinf Hill slope (GR values) R-squared sigmoid fit (GR values) P-value sigmoid fit (GR values) R-squared flat fit (GR values) IC50 Emax AUC EC50 Einf Hill slope (relative cell counts) R-squared sigmoid fit (relative cell counts) P-value sigmoid fit (relative cell counts) R-squared flat fit (relative cell counts)
BT-20 AS605240 2 72
sigmoid
sigmoid
BT20 AS-605240 0 2 72
 8 1.846
4509270.0
0.729
0.203
320.0
0.31
0.101
0.845
0.00373
NA
4.4e+12
0.764
0.821
56.5
0.46
0.101
0.843
0.00388
NA
HCC70 PIK-93 2 72
sigmoid
sigmoid
HCC70 PIK-93 0 2 72
 8 1.705
4.34
0.647
0.0132
9.3
-1.0
1.44
0.888
0.0014
NA
6.01
0.718
0.991
6.01
0.0
1.49
0.872
0.00208
NA
HCC38 MK2206 1 72
sigmoid
sigmoid
HCC38 MK-2206 0 1 72
 8 1.789
19.4
0.698
0.0995
320.0
-0.949
0.38
0.956
8.33e-05
NA
61.8
0.746
0.914
61.8
0.0
0.386
0.951
0.000115
NA
Hs 578T AZD-6482 2
sigmoid
sigmoid
Hs578T AZD6482 2
 8 2.508
6.35
0.602
0.121
74.8
-1.0
0.445
0.998
1.12e-08
NA
6.4
0.573
0.86
6.4
0.0
0.475
0.996
6.36e-08
NA
BT-549 PIK-93 3 72
sigmoid
sigmoid
BT549 PIK-93 0 3 72
 8 1.807
20.1
0.719
0.0848
231.0
-1.0
0.45
0.716
0.0229
NA
67.9
0.761
0.925
67.9
0.0
0.431
0.686
0.0309
NA
BT-549 Sirolimus 1 72
sigmoid
sigmoid
BT549 rapamycin 0 1 72
 8 1.817
3.62
0.51
0.438
0.000148
0.318
0.1
0.87
0.00218
NA
506850.0
0.6
0.638
8.82e-05
0.447
0.1
0.8
0.00802
NA
HCC38 PIK-93 1 72
sigmoid
sigmoid
HCC38 PIK-93 0 1 72
 8 1.741
5.24
0.61
0.0782
24.5
-1.0
0.713
0.982
6.07e-06
NA
9.93
0.686
0.935
9.93
0.0
0.729
0.979
9.08e-06
NA