Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | ZSTK474 | 3 | 72 | 0.01 | 3124.3 | 2931.3 | 517.3 | -2.0 | 1.050 | 1.070 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | ZSTK474 | 3 | 72 | 0.032 | 2965.0 | 2931.3 | 517.3 | -1.49 | 1.010 | 1.010 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | ZSTK474 | 3 | 72 | 0.1 | 2439.8 | 2931.3 | 517.3 | -1.0 | 0.859 | 0.832 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | ZSTK474 | 3 | 72 | 0.32 | 1617.8 | 2931.3 | 517.3 | -0.495 | 0.577 | 0.552 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | ZSTK474 | 3 | 72 | 1.0 | 1101.3 | 2931.3 | 517.3 | 0.0 | 0.352 | 0.376 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | ZSTK474 | 3 | 72 | 3.2 | 776.5 | 2931.3 | 517.3 | 0.505 | 0.176 | 0.265 | 2.502 | HCC70 ZSTK474 0 3 72 |