Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | BX-912 | 2 | 72 | 0.032 | 2615.0 | 2337.5 | 722.8 | -1.49 | 1.140 | 1.120 | 1.693 | HCC70 BX912 0 2 72 |
| BT-20 | ZSTK474 | 1 | 72 | 0.032 | 6289.3 | 5537.8 | 1443.3 | -1.49 | 1.140 | 1.140 | 1.940 | BT20 ZSTK474 0 1 |
| BT-549 | MK2206 | 2 | 72 | 1.0 | 5246.0 | 4569.8 | 1249.6 | 0.0 | 1.150 | 1.150 | 1.871 | BT549 MK2206 0 2 72 |
| BT-549 | MK2206 | 1 | 72 | 3.2 | 6334.0 | 5457.0 | 1554.9 | 0.505 | 1.170 | 1.160 | 1.811 | BT549 MK2206 0 1 72 |
| BT-549 | MK2206 | 2 | 72 | 3.2 | 6181.5 | 4569.8 | 1249.6 | 0.505 | 1.350 | 1.350 | 1.871 | BT549 MK2206 0 2 72 |
| BT-549 | MK2206 | 3 | 72 | 3.2 | 5138.0 | 3781.8 | 1175.8 | 0.505 | 1.400 | 1.360 | 1.685 | BT549 MK2206 0 3 72 |