Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | AS605240 | 3 | 72 | 0.1 | 3083.5 | 2994.3 | 1180.5 | -1.0 | 1.040 | 1.030 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 0.32 | 3034.0 | 2994.3 | 1180.5 | -0.495 | 1.020 | 1.010 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 0.032 | 3071.8 | 2994.3 | 1180.5 | -1.49 | 1.040 | 1.030 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 0.0032 | 2991.0 | 2994.3 | 1180.5 | -2.49 | 0.998 | 0.999 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 0.001 | 3065.8 | 2994.3 | 1180.5 | -3.0 | 1.040 | 1.020 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 0.01 | 3058.0 | 2994.3 | 1180.5 | -2.0 | 1.030 | 1.020 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC38 | AS605240 | 3 | 72 | 1.0 | 2963.5 | 2994.3 | 1180.5 | 0.0 | 0.985 | 0.990 | 1.343 | HCC38 AS605240 0 3 72 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 2067.3 | 3250.8 | 1279.8 | -1.0 | 0.428 | 0.636 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 0.032 | 2393.3 | 3250.8 | 1279.8 | -1.49 | 0.593 | 0.736 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 0.32 | 1648.5 | 3250.8 | 1279.8 | -0.495 | 0.207 | 0.507 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 1545.0 | 3250.8 | 1279.8 | 0.0 | 0.150 | 0.475 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 0.0032 | 2995.0 | 3250.8 | 1279.8 | -2.49 | 0.882 | 0.921 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 3.2 | 1655.5 | 3250.8 | 1279.8 | 0.505 | 0.211 | 0.509 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 3349.0 | 3250.8 | 1279.8 | -3.0 | 1.040 | 1.030 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | Torin1 | 1 | 72 | 0.01 | 2614.0 | 3250.8 | 1279.8 | -2.0 | 0.701 | 0.804 | 1.345 | HCC70 Torin1 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 1.0 | 3187.8 | 3263.0 | 1279.8 | 0.0 | 0.966 | 0.977 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | GDC-0980 | 1 | 72 | 3.2 | 772.8 | 3261.8 | 1279.8 | 0.505 | -0.312 | 0.237 | 1.350 | HCC70 GDC0980 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 3.2 | 3021.3 | 3263.0 | 1279.8 | 0.505 | 0.889 | 0.926 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 0.01 | 3132.8 | 3263.0 | 1279.8 | -2.0 | 0.941 | 0.960 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 0.032 | 3335.5 | 3263.0 | 1279.8 | -1.49 | 1.030 | 1.020 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | GDC-0980 | 1 | 72 | 0.1 | 2676.5 | 3261.8 | 1279.8 | -1.0 | 0.727 | 0.821 | 1.350 | HCC70 GDC0980 0 1 72 |
| HCC70 | GDC-0980 | 1 | 72 | 0.32 | 1777.3 | 3261.8 | 1279.8 | -0.495 | 0.275 | 0.545 | 1.350 | HCC70 GDC0980 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 0.1 | 3346.5 | 3263.0 | 1279.8 | -1.0 | 1.040 | 1.030 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | KIN001-244 | 1 | 72 | 0.001 | 3292.8 | 3263.0 | 1279.8 | -3.0 | 1.010 | 1.010 | 1.350 | HCC70 KIN001-244 0 1 72 |
| HCC70 | GDC-0980 | 1 | 72 | 0.032 | 3182.3 | 3261.8 | 1279.8 | -1.49 | 0.964 | 0.976 | 1.350 | HCC70 GDC0980 0 1 72 |