Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | Torin1 | 3 | 72 | 0.1 | 1495.0 | 3204.3 | 1180.5 | -1.0 | 0.178 | 0.467 | 1.441 | HCC38 Torin1 0 3 72 |
| HCC38 | Torin1 | 3 | 72 | 0.01 | 2478.8 | 3204.3 | 1180.5 | -2.0 | 0.674 | 0.774 | 1.441 | HCC38 Torin1 0 3 72 |
| HCC38 | Torin1 | 3 | 72 | 3.2 | 853.0 | 3204.3 | 1180.5 | 0.505 | -0.202 | 0.266 | 1.441 | HCC38 Torin1 0 3 72 |
| HCC38 | Torin1 | 3 | 72 | 0.032 | 1952.3 | 3204.3 | 1180.5 | -1.49 | 0.418 | 0.609 | 1.441 | HCC38 Torin1 0 3 72 |
| HCC38 | Torin1 | 3 | 72 | 0.32 | 1196.8 | 3204.3 | 1180.5 | -0.495 | 0.010 | 0.373 | 1.441 | HCC38 Torin1 0 3 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.001 | 3210.5 | 3477.0 | 1279.8 | -3.0 | 0.892 | 0.923 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.0032 | 3227.0 | 3477.0 | 1279.8 | -2.49 | 0.899 | 0.928 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.01 | 3291.8 | 3477.0 | 1279.8 | -2.0 | 0.925 | 0.947 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.032 | 3233.5 | 3477.0 | 1279.8 | -1.49 | 0.902 | 0.930 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.1 | 3326.3 | 3477.0 | 1279.8 | -1.0 | 0.939 | 0.957 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 0.32 | 3159.3 | 3477.0 | 1279.8 | -0.495 | 0.871 | 0.909 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 1.0 | 3037.5 | 3477.0 | 1279.8 | 0.0 | 0.821 | 0.874 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC70 | PIK-93 | 1 | 72 | 3.2 | 2256.0 | 3477.0 | 1279.8 | 0.505 | 0.482 | 0.649 | 1.442 | HCC70 PIK93 0 1 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.001 | 3140.0 | 3209.8 | 1180.5 | -3.0 | 0.970 | 0.978 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 3.2 | 2937.0 | 3209.8 | 1180.5 | 0.505 | 0.881 | 0.915 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.0032 | 3108.3 | 3209.8 | 1180.5 | -2.49 | 0.956 | 0.968 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.1 | 2981.5 | 3209.8 | 1180.5 | -1.0 | 0.900 | 0.929 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.32 | 3046.3 | 3209.8 | 1180.5 | -0.495 | 0.929 | 0.949 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.01 | 3029.3 | 3209.8 | 1180.5 | -2.0 | 0.921 | 0.944 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 1.0 | 2870.5 | 3209.8 | 1180.5 | 0.0 | 0.851 | 0.894 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC38 | CAL-101 | 3 | 72 | 0.032 | 3105.3 | 3209.8 | 1180.5 | -1.49 | 0.955 | 0.967 | 1.443 | HCC38 CAL101 0 3 72 |
| HCC70 | MK2206 | 1 | 72 | 0.0032 | 3306.0 | 3483.3 | 1279.8 | -2.49 | 0.929 | 0.949 | 1.444 | HCC70 MK2206 0 1 72 |
| HCC70 | MK2206 | 1 | 72 | 1.0 | 1648.0 | 3483.3 | 1279.8 | 0.0 | 0.191 | 0.473 | 1.444 | HCC70 MK2206 0 1 72 |
| HCC70 | MK2206 | 1 | 72 | 3.2 | 1231.0 | 3483.3 | 1279.8 | 0.505 | -0.027 | 0.353 | 1.444 | HCC70 MK2206 0 1 72 |
| HCC70 | MK2206 | 1 | 72 | 0.32 | 2261.3 | 3483.3 | 1279.8 | -0.495 | 0.483 | 0.649 | 1.444 | HCC70 MK2206 0 1 72 |