Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | MK2206 | 2 | 72 | 3.2 | 8994.8 | 11692.5 | 1643.3 | 0.505 | 0.823 | 0.769 | 2.831 | HCC1806 MK2206 0 2 72 |
| BT-549 | KIN001-244 | 2 | 72 | 3.2 | 4208.3 | 4727.5 | 1249.6 | 0.505 | 0.882 | 0.890 | 1.920 | BT549 KIN001-244 0 2 72 |
| HCC1806 | KIN001-244 | 2 | 72 | 3.2 | 11439.0 | 11660.3 | 1643.3 | 0.505 | 0.986 | 0.981 | 2.827 | HCC1806 KIN001-244 0 2 72 |
| HCC38 | Sirolimus | 1 | 72 | 3.2 | 2698.5 | 4278.0 | 1295.5 | 0.505 | 0.531 | 0.631 | 1.723 | HCC38 Rapamycin 0 1 72 |
| HCC70 | KIN001-244 | 3 | 72 | 3.2 | 2581.3 | 2870.0 | 517.3 | 0.505 | 0.916 | 0.899 | 2.472 | HCC70 KIN001-244 0 3 72 |
| Hs 578T | TGX221 | 1 | 72 | 3.2 | 2506.5 | 3538.5 | 873.1 | 0.505 | 0.686 | 0.708 | 2.019 | Hs578T TGX221 1 |