Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | ZSTK474 | 1 | 72 | 0.0032 | 5912.0 | 5537.8 | 1443.3 | -2.49 | 1.070 | 1.070 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 1 | 72 | 0.032 | 6289.3 | 5537.8 | 1443.3 | -1.49 | 1.140 | 1.140 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 1 | 72 | 1.0 | 2728.0 | 5537.8 | 1443.3 | 0.0 | 0.388 | 0.493 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 1 | 72 | 0.32 | 4643.0 | 5537.8 | 1443.3 | -0.495 | 0.826 | 0.838 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 1 | 72 | 0.1 | 6021.3 | 5537.8 | 1443.3 | -1.0 | 1.090 | 1.090 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 2 | 72 | 3.2 | 699.5 | 3516.3 | 1018.6 | 0.505 | -0.190 | 0.199 | 1.787 | BT20 ZSTK474 0 2 |
| BT-20 | ZSTK474 | 3 | 72 | 0.001 | 3277.0 | 3579.5 | 586.9 | -3.0 | 0.933 | 0.915 | 2.609 | BT20 ZSTK474 0 3 |
| BT-20 | ZSTK474 | 3 | 72 | 0.1 | 2816.5 | 3579.5 | 586.9 | -1.0 | 0.824 | 0.787 | 2.609 | BT20 ZSTK474 0 3 |
| BT-20 | ZSTK474 | 1 | 72 | 0.001 | 5978.0 | 5537.8 | 1443.3 | -3.0 | 1.080 | 1.080 | 1.940 | BT20 ZSTK474 0 1 |
| BT-549 | ZSTK474 | 1 | 72 | 0.01 | 5438.8 | 5649.0 | 1554.9 | -2.0 | 0.960 | 0.963 | 1.861 | BT549 ZSTK474 0 1 72 |
| BT-549 | ZSTK474 | 1 | 72 | 0.032 | 5268.8 | 5649.0 | 1554.9 | -1.49 | 0.926 | 0.933 | 1.861 | BT549 ZSTK474 0 1 72 |
| BT-549 | ZSTK474 | 1 | 72 | 0.32 | 3782.8 | 5649.0 | 1554.9 | -0.495 | 0.612 | 0.670 | 1.861 | BT549 ZSTK474 0 1 72 |
| BT-549 | ZSTK474 | 1 | 72 | 1.0 | 2875.0 | 5649.0 | 1554.9 | 0.0 | 0.391 | 0.509 | 1.861 | BT549 ZSTK474 0 1 72 |
| BT-20 | ZSTK474 | 2 | 72 | 1.0 | 1046.8 | 3516.3 | 1018.6 | 0.0 | 0.015 | 0.298 | 1.787 | BT20 ZSTK474 0 2 |
| BT-549 | ZSTK474 | 2 | 72 | 0.01 | 4539.3 | 4867.8 | 1249.6 | -2.0 | 0.930 | 0.933 | 1.962 | BT549 ZSTK474 0 2 72 |
| BT-549 | ZSTK474 | 2 | 72 | 0.1 | 4170.3 | 4867.8 | 1249.6 | -1.0 | 0.848 | 0.857 | 1.962 | BT549 ZSTK474 0 2 72 |
| BT-549 | ZSTK474 | 2 | 72 | 0.32 | 3342.8 | 4867.8 | 1249.6 | -0.495 | 0.651 | 0.687 | 1.962 | BT549 ZSTK474 0 2 72 |
| BT-20 | ZSTK474 | 2 | 72 | 0.0032 | 3396.8 | 3516.3 | 1018.6 | -2.49 | 0.962 | 0.966 | 1.787 | BT20 ZSTK474 0 2 |
| BT-20 | ZSTK474 | 2 | 72 | 0.001 | 3212.8 | 3516.3 | 1018.6 | -3.0 | 0.902 | 0.914 | 1.787 | BT20 ZSTK474 0 2 |
| BT-20 | ZSTK474 | 2 | 72 | 0.01 | 3448.5 | 3516.3 | 1018.6 | -2.0 | 0.978 | 0.981 | 1.787 | BT20 ZSTK474 0 2 |
| BT-20 | ZSTK474 | 2 | 72 | 0.032 | 3425.3 | 3516.3 | 1018.6 | -1.49 | 0.971 | 0.974 | 1.787 | BT20 ZSTK474 0 2 |
| BT-20 | ZSTK474 | 1 | 72 | 0.01 | 6056.8 | 5537.8 | 1443.3 | -2.0 | 1.090 | 1.090 | 1.940 | BT20 ZSTK474 0 1 |
| BT-20 | ZSTK474 | 1 | 72 | 3.2 | 1504.8 | 5537.8 | 1443.3 | 0.505 | 0.022 | 0.272 | 1.940 | BT20 ZSTK474 0 1 |
| HCC38 | ZSTK474 | 1 | 72 | 0.0032 | 4297.0 | 4334.5 | 1295.5 | -2.49 | 0.990 | 0.991 | 1.742 | HCC38 ZSTK474 0 1 72 |
| HCC38 | ZSTK474 | 1 | 72 | 0.001 | 4237.8 | 4334.5 | 1295.5 | -3.0 | 0.974 | 0.978 | 1.742 | HCC38 ZSTK474 0 1 72 |