Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | WYE-125132 | 3 | 72 | 1.0 | 1048.5 | 4195.3 | 571.3 | 0.0 | 0.235 | 0.250 | 2.876 | Hs578T WYE125132 3 |
| BT-20 | Dactolisib | 3 | 72 | 1.0 | 727.5 | 3141.3 | 586.9 | 0.0 | 0.093 | 0.232 | 2.420 | BT20 BEZ235 0 3 |
| HCC70 | ZSTK474 | 3 | 72 | 1.0 | 1101.3 | 2931.3 | 517.3 | 0.0 | 0.352 | 0.376 | 2.502 | HCC70 ZSTK474 0 3 72 |
| HCC70 | Omipalisib | 3 | 72 | 1.0 | 228.8 | 2841.5 | 517.3 | 0.0 | -0.283 | 0.081 | 2.458 | HCC70 GSK458 0 3 72 |
| Hs 578T | TGX221 | 1 | 72 | 1.0 | 2869.0 | 3538.5 | 873.1 | 0.0 | 0.803 | 0.811 | 2.019 | Hs578T TGX221 1 |
| HCC1806 | Omipalisib | 2 | 72 | 1.0 | 1813.3 | 11840.0 | 1643.3 | 0.0 | 0.035 | 0.153 | 2.849 | HCC1806 GSK458 0 2 72 |