Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | WYE-125132 | 2 | 72 | 3.2 | 1379.5 | 2308.5 | 722.8 | 0.505 | 0.471 | 0.598 | 1.675 | HCC70 WYE125132 0 2 72 |
| HCC70 | WYE-125132 | 2 | 72 | 1.0 | 1402.5 | 2308.5 | 722.8 | 0.0 | 0.485 | 0.608 | 1.675 | HCC70 WYE125132 0 2 72 |
| HCC70 | WYE-125132 | 2 | 72 | 0.32 | 1397.0 | 2308.5 | 722.8 | -0.495 | 0.482 | 0.605 | 1.675 | HCC70 WYE125132 0 2 72 |
| HCC70 | WYE-125132 | 2 | 72 | 0.1 | 1462.3 | 2308.5 | 722.8 | -1.0 | 0.523 | 0.633 | 1.675 | HCC70 WYE125132 0 2 72 |
| HCC70 | WYE-125132 | 2 | 72 | 0.032 | 1724.8 | 2308.5 | 722.8 | -1.49 | 0.681 | 0.747 | 1.675 | HCC70 WYE125132 0 2 72 |
| HCC70 | WYE-125132 | 2 | 72 | 0.0032 | 2162.8 | 2308.5 | 722.8 | -2.49 | 0.924 | 0.937 | 1.675 | HCC70 WYE125132 0 2 72 |