Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
---|---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | Omipalisib | 1 | 72 | 3.2 | 95.5 | 6095.3 | 1443.3 | 0.505 | -0.729 | 0.016 | 2.078 | BT20 GSK458 0 1 |
HCC70 | Torin2 | 1 | 72 | 3.2 | 212.0 | 3294.3 | 1279.8 | 0.505 | -0.732 | 0.064 | 1.364 | HCC70 Torin2 0 1 72 |
BT-20 | Torin2 | 1 | 72 | 3.2 | 96.0 | 5846.0 | 1443.3 | 0.505 | -0.739 | 0.016 | 2.018 | BT20 Torin2 0 1 |
BT-20 | Torin2 | 2 | 72 | 3.2 | 85.5 | 3386.5 | 1018.6 | 0.505 | -0.761 | 0.025 | 1.733 | BT20 Torin2 0 2 |
HCC70 | Omipalisib | 1 | 72 | 3.2 | 159.3 | 3280.0 | 1279.8 | 0.505 | -0.785 | 0.049 | 1.358 | HCC70 GSK458 0 1 72 |
BT-20 | Omipalisib | 2 | 72 | 3.2 | 65.0 | 3349.0 | 1018.6 | 0.505 | -0.799 | 0.019 | 1.717 | BT20 GSK458 0 2 |