Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | AS605240 | 1 | 72 | 0.032 | 11947.8 | 11546.3 | 1742.8 | -1.49 | 1.030 | 1.030 | 2.728 | HCC1806 AS605240 0 1 72 |
| HCC1806 | AS605240 | 1 | 72 | 0.32 | 11293.3 | 11546.3 | 1742.8 | -0.495 | 0.984 | 0.978 | 2.728 | HCC1806 AS605240 0 1 72 |
| HCC38 | AS605240 | 2 | 72 | 0.01 | 3011.8 | 3173.5 | 690.5 | -2.0 | 0.953 | 0.949 | 2.200 | HCC38 AS605240 0 2 72 |
| HCC70 | AS605240 | 3 | 72 | 0.01 | 2809.8 | 2821.5 | 517.3 | -2.0 | 0.997 | 0.996 | 2.447 | HCC70 AS605240 0 3 72 |
| BT-549 | AS605240 | 2 | 72 | 0.032 | 4901.5 | 4866.0 | 1249.6 | -1.49 | 1.010 | 1.010 | 1.961 | BT549 AS605240 0 2 72 |
| BT-20 | AS605240 | 1 | 72 | 0.032 | 5869.3 | 6371.0 | 1443.3 | -1.49 | 0.925 | 0.921 | 2.142 | BT20 AS605240 0 1 |
| HCC70 | AS605240 | 1 | 72 | 1.0 | 2458.0 | 3347.8 | 1279.8 | 0.0 | 0.601 | 0.734 | 1.387 | HCC70 AS605240 0 1 72 |
| HCC1806 | AS605240 | 1 | 72 | 1.0 | 10421.8 | 11546.3 | 1742.8 | 0.0 | 0.926 | 0.903 | 2.728 | HCC1806 AS605240 0 1 72 |
| BT-20 | AS605240 | 3 | 72 | 0.032 | 3388.8 | 3575.0 | 586.9 | -1.49 | 0.959 | 0.948 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.32 | 3050.3 | 3575.0 | 586.9 | -0.495 | 0.882 | 0.853 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 3.2 | 2896.3 | 3575.0 | 586.9 | 0.505 | 0.845 | 0.810 | 2.607 | BT20 AS605240 0 3 |
| BT-549 | AS605240 | 3 | 72 | 1.0 | 3682.3 | 4082.5 | 1175.8 | 0.0 | 0.888 | 0.902 | 1.796 | BT549 AS605240 0 3 72 |
| BT-20 | AS605240 | 3 | 72 | 0.1 | 3148.5 | 3575.0 | 586.9 | -1.0 | 0.905 | 0.881 | 2.607 | BT20 AS605240 0 3 |
| HCC1806 | AS605240 | 1 | 72 | 0.01 | 11617.5 | 11546.3 | 1742.8 | -2.0 | 1.000 | 1.010 | 2.728 | HCC1806 AS605240 0 1 72 |
| HCC1806 | AS605240 | 1 | 72 | 0.0032 | 11624.3 | 11546.3 | 1742.8 | -2.49 | 1.000 | 1.010 | 2.728 | HCC1806 AS605240 0 1 72 |
| HCC1806 | AS605240 | 1 | 72 | 0.001 | 11618.8 | 11546.3 | 1742.8 | -3.0 | 1.000 | 1.010 | 2.728 | HCC1806 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.001 | 5384.8 | 5429.5 | 1554.9 | -3.0 | 0.991 | 0.992 | 1.804 | BT549 AS605240 0 1 72 |
| BT-20 | AS605240 | 3 | 72 | 0.001 | 3319.5 | 3575.0 | 586.9 | -3.0 | 0.944 | 0.929 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.01 | 3575.3 | 3575.0 | 586.9 | -2.0 | 1.000 | 1.000 | 2.607 | BT20 AS605240 0 3 |
| BT-549 | AS605240 | 2 | 72 | 1.0 | 4471.0 | 4866.0 | 1249.6 | 0.0 | 0.916 | 0.919 | 1.961 | BT549 AS605240 0 2 72 |
| BT-549 | AS605240 | 2 | 72 | 0.0032 | 4819.5 | 4866.0 | 1249.6 | -2.49 | 0.990 | 0.990 | 1.961 | BT549 AS605240 0 2 72 |
| BT-20 | AS605240 | 3 | 72 | 0.0032 | 3254.5 | 3575.0 | 586.9 | -2.49 | 0.929 | 0.910 | 2.607 | BT20 AS605240 0 3 |
| BT-549 | AS605240 | 3 | 72 | 0.001 | 4064.3 | 4082.5 | 1175.8 | -3.0 | 0.995 | 0.996 | 1.796 | BT549 AS605240 0 3 72 |
| BT-549 | AS605240 | 3 | 72 | 0.0032 | 3907.5 | 4082.5 | 1175.8 | -2.49 | 0.952 | 0.957 | 1.796 | BT549 AS605240 0 3 72 |
| HCC38 | AS605240 | 2 | 72 | 0.0032 | 3249.3 | 3173.5 | 690.5 | -2.49 | 1.020 | 1.020 | 2.200 | HCC38 AS605240 0 2 72 |