Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AZD8055 | 1 | 72 | 1.0 | 2287.8 | 5941.5 | 1443.3 | 0.0 | 0.253 | 0.385 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.32 | 2468.3 | 5941.5 | 1443.3 | -0.495 | 0.301 | 0.415 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.1 | 2922.5 | 5941.5 | 1443.3 | -1.0 | 0.413 | 0.492 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.032 | 3968.5 | 5941.5 | 1443.3 | -1.49 | 0.641 | 0.668 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.0032 | 5387.5 | 5941.5 | 1443.3 | -2.49 | 0.906 | 0.907 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.01 | 4836.5 | 5941.5 | 1443.3 | -2.0 | 0.808 | 0.814 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 2 | 72 | 0.32 | 674.3 | 3421.5 | 1018.6 | -0.495 | -0.210 | 0.197 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 1.0 | 575.0 | 3421.5 | 1018.6 | 0.0 | -0.279 | 0.168 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 3.2 | 419.0 | 3421.5 | 1018.6 | 0.505 | -0.398 | 0.122 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 0.0032 | 2842.0 | 3421.5 | 1018.6 | -2.49 | 0.799 | 0.831 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 0.01 | 2548.3 | 3421.5 | 1018.6 | -2.0 | 0.690 | 0.745 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 0.032 | 1518.3 | 3421.5 | 1018.6 | -1.49 | 0.257 | 0.444 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 0.1 | 929.8 | 3421.5 | 1018.6 | -1.0 | -0.051 | 0.272 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 2 | 72 | 0.001 | 3041.5 | 3421.5 | 1018.6 | -3.0 | 0.870 | 0.889 | 1.748 | BT20 AZD8055 0 2 |
| BT-20 | AZD8055 | 3 | 72 | 0.32 | 709.0 | 3441.0 | 586.9 | -0.495 | 0.077 | 0.206 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 1.0 | 616.8 | 3441.0 | 586.9 | 0.0 | 0.020 | 0.179 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 3.2 | 529.0 | 3441.0 | 586.9 | 0.505 | -0.040 | 0.154 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 0.1 | 1053.0 | 3441.0 | 586.9 | -1.0 | 0.257 | 0.306 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 0.032 | 1649.5 | 3441.0 | 586.9 | -1.49 | 0.499 | 0.479 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 0.01 | 2824.3 | 3441.0 | 586.9 | -2.0 | 0.851 | 0.821 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 0.0032 | 2862.0 | 3441.0 | 586.9 | -2.49 | 0.861 | 0.832 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | AZD8055 | 3 | 72 | 0.001 | 3103.8 | 3441.0 | 586.9 | -3.0 | 0.921 | 0.902 | 2.552 | BT20 AZD8055 0 3 |
| BT-20 | Dactolisib | 1 | 72 | 1.0 | 1253.8 | 5998.3 | 1443.3 | 0.0 | -0.066 | 0.209 | 2.055 | BT20 BEZ235 0 1 |
| BT-20 | Dactolisib | 1 | 72 | 0.32 | 1891.3 | 5998.3 | 1443.3 | -0.495 | 0.141 | 0.315 | 2.055 | BT20 BEZ235 0 1 |
| BT-20 | Dactolisib | 1 | 72 | 0.1 | 2350.5 | 5998.3 | 1443.3 | -1.0 | 0.268 | 0.392 | 2.055 | BT20 BEZ235 0 1 |