Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AZD-6482 | 1 | 72 | 0.32 | 5060.8 | 5948.8 | 1443.3 | -0.495 | 0.848 | 0.851 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.01 | 5842.5 | 5948.8 | 1443.3 | -2.0 | 0.982 | 0.982 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.032 | 5770.3 | 5948.8 | 1443.3 | -1.49 | 0.970 | 0.970 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.1 | 5531.0 | 5948.8 | 1443.3 | -1.0 | 0.930 | 0.930 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.001 | 5532.3 | 5948.8 | 1443.3 | -3.0 | 0.930 | 0.930 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 3.2 | 2032.7 | 5948.8 | 1443.3 | 0.505 | 0.182 | 0.342 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.0032 | 5542.0 | 5948.8 | 1443.3 | -2.49 | 0.932 | 0.932 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 2 | 72 | 0.1 | 2717.8 | 3186.5 | 1018.6 | -1.0 | 0.816 | 0.853 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 0.32 | 2528.8 | 3186.5 | 1018.6 | -0.495 | 0.738 | 0.794 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 1.0 | 1651.0 | 3186.5 | 1018.6 | 0.0 | 0.341 | 0.518 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 0.01 | 2863.5 | 3186.5 | 1018.6 | -2.0 | 0.874 | 0.899 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 0.032 | 2798.3 | 3186.5 | 1018.6 | -1.49 | 0.848 | 0.878 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 0.0032 | 2774.5 | 3186.5 | 1018.6 | -2.49 | 0.839 | 0.871 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 3.2 | 1061.3 | 3186.5 | 1018.6 | 0.505 | 0.025 | 0.333 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 2 | 72 | 0.001 | 2737.3 | 3186.5 | 1018.6 | -3.0 | 0.824 | 0.859 | 1.645 | BT20 AZD6482 0 2 |
| BT-20 | AZD-6482 | 3 | 72 | 0.0032 | 3136.8 | 3560.8 | 586.9 | -2.49 | 0.905 | 0.881 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 0.001 | 3256.8 | 3560.8 | 586.9 | -3.0 | 0.933 | 0.915 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 1.0 | 2162.8 | 3560.8 | 586.9 | 0.0 | 0.651 | 0.607 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 3.2 | 1162.3 | 3560.8 | 586.9 | 0.505 | 0.300 | 0.326 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 0.01 | 3282.5 | 3560.8 | 586.9 | -2.0 | 0.938 | 0.922 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 0.032 | 3397.0 | 3560.8 | 586.9 | -1.49 | 0.964 | 0.954 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 0.1 | 3118.3 | 3560.8 | 586.9 | -1.0 | 0.901 | 0.876 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD-6482 | 3 | 72 | 0.32 | 2758.0 | 3560.8 | 586.9 | -0.495 | 0.813 | 0.775 | 2.601 | BT20 AZD6482 0 3 |
| BT-20 | AZD8055 | 1 | 72 | 3.2 | 2067.3 | 5941.5 | 1443.3 | 0.505 | 0.192 | 0.348 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.001 | 5501.0 | 5941.5 | 1443.3 | -3.0 | 0.926 | 0.926 | 2.041 | BT20 AZD8055 0 1 |