Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
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HCC1806 | WYE-125132 | 1 | 72 | 0.032 | 8601.3 | 12050.8 | 1742.8 | -1.49 | 0.772 | 0.714 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 1 | 72 | 1.0 | 5290.0 | 12050.8 | 1742.8 | 0.0 | 0.489 | 0.439 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 2 | 72 | 1.0 | 5290.0 | 12050.8 | 1643.3 | 0.0 | 0.502 | 0.439 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 1 | 72 | 0.01 | 10352.8 | 12050.8 | 1742.8 | -2.0 | 0.894 | 0.859 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 1 | 72 | 0.1 | 6801.8 | 12050.8 | 1742.8 | -1.0 | 0.629 | 0.564 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 2 | 72 | 3.2 | 5062.8 | 12050.8 | 1643.3 | 0.505 | 0.479 | 0.420 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.1 | 6801.8 | 12050.8 | 1273.3 | -1.0 | 0.677 | 0.564 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.1 | 6801.8 | 12050.8 | 1643.3 | -1.0 | 0.639 | 0.564 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.32 | 5594.8 | 12050.8 | 1273.3 | -0.495 | 0.579 | 0.464 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 3 | 72 | 1.0 | 5290.0 | 12050.8 | 1273.3 | 0.0 | 0.552 | 0.439 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 3 | 72 | 3.2 | 5062.8 | 12050.8 | 1273.3 | 0.505 | 0.531 | 0.420 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.001 | 11365.0 | 12050.8 | 1273.3 | -3.0 | 0.964 | 0.943 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.001 | 11365.0 | 12050.8 | 1643.3 | -3.0 | 0.960 | 0.943 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.0032 | 11072.0 | 12050.8 | 1273.3 | -2.49 | 0.948 | 0.919 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.0032 | 11072.0 | 12050.8 | 1643.3 | -2.49 | 0.942 | 0.919 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.01 | 10352.8 | 12050.8 | 1273.3 | -2.0 | 0.908 | 0.859 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 1 | 72 | 0.001 | 11365.0 | 12050.8 | 1742.8 | -3.0 | 0.958 | 0.943 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.032 | 8601.3 | 12050.8 | 1643.3 | -1.49 | 0.779 | 0.714 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.01 | 10352.8 | 12050.8 | 1643.3 | -2.0 | 0.897 | 0.859 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 2 | 72 | 0.32 | 5594.8 | 12050.8 | 1643.3 | -0.495 | 0.531 | 0.464 | 2.874 | HCC1806 WYE125132 0 2 72 |
HCC1806 | WYE-125132 | 3 | 72 | 0.032 | 8601.3 | 12050.8 | 1273.3 | -1.49 | 0.802 | 0.714 | 3.242 | HCC1806 WYE125132 0 3 72 |
HCC1806 | WYE-125132 | 1 | 72 | 3.2 | 5062.8 | 12050.8 | 1742.8 | 0.505 | 0.466 | 0.420 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | WYE-125132 | 1 | 72 | 0.0032 | 11072.0 | 12050.8 | 1742.8 | -2.49 | 0.940 | 0.919 | 2.790 | HCC1806 WYE125132 0 1 72 |
HCC1806 | Everolimus | 3 | 72 | 0.0032 | 9348.8 | 12020.5 | 1273.3 | -2.49 | 0.851 | 0.778 | 3.239 | HCC1806 Everolimus 0 3 72 |
HCC1806 | Everolimus | 3 | 72 | 0.001 | 10053.0 | 12020.5 | 1273.3 | -3.0 | 0.893 | 0.836 | 3.239 | HCC1806 Everolimus 0 3 72 |