Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 MK2206 2 72
0.001
 11458.3 11692.5 1643.3
-3.0
 0.986 0.980 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
0.0032
 11472.3 11692.5 1643.3
-2.49
 0.987 0.981 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
0.01
 11541.0 11692.5 1643.3
-2.0
 0.991 0.987 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
0.032
 11428.3 11692.5 1643.3
-1.49
 0.984 0.977 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
0.1
 11113.3 11692.5 1643.3
-1.0
 0.964 0.950 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
0.32
 10467.5 11692.5 1643.3
-0.495
 0.923 0.895 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
1.0
 10180.5 11692.5 1643.3
0.0
 0.905 0.871 2.831
HCC1806 MK2206 0 2 72
HCC1806 MK2206 2 72
3.2
 8994.8 11692.5 1643.3
0.505
 0.823 0.769 2.831
HCC1806 MK2206 0 2 72
HCC1806 PI103 2 72
0.001
 10973.0 11113.3 1643.3
-3.0
 0.991 0.987 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
0.0032
 11168.3 11113.3 1643.3
-2.49
 1.000 1.000 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
0.01
 11663.8 11113.3 1643.3
-2.0
 1.040 1.050 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
0.032
 11750.3 11113.3 1643.3
-1.49
 1.040 1.060 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
0.1
 10951.8 11113.3 1643.3
-1.0
 0.989 0.985 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
0.32
 10874.3 11113.3 1643.3
-0.495
 0.984 0.978 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
1.0
 10453.3 11113.3 1643.3
0.0
 0.956 0.941 2.758
HCC1806 PI103 0 2 72
HCC1806 PI103 2 72
3.2
 9624.3 11113.3 1643.3
0.505
 0.898 0.866 2.758
HCC1806 PI103 0 2 72
HCC1806 PIK-93 2 72
0.001
 11663.0 11752.8 1643.3
-3.0
 0.995 0.992 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
0.0032
 11204.3 11752.8 1643.3
-2.49
 0.967 0.953 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
0.01
 11234.5 11752.8 1643.3
-2.0
 0.968 0.956 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
0.032
 11478.5 11752.8 1643.3
-1.49
 0.983 0.977 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
0.1
 11468.5 11752.8 1643.3
-1.0
 0.983 0.976 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
0.32
 11233.8 11752.8 1643.3
-0.495
 0.968 0.956 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
1.0
 10760.3 11752.8 1643.3
0.0
 0.939 0.916 2.838
HCC1806 PIK93 0 2 72
HCC1806 PIK-93 2 72
3.2
 9528.0 11752.8 1643.3
0.505
 0.857 0.811 2.838
HCC1806 PIK93 0 2 72
HCC1806 Sirolimus 2 72
0.001
 9616.0 12104.5 1643.3
-3.0
 0.846 0.794 2.881
HCC1806 Rapamycin 0 2 72