LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | 180614_BG_02 | 1071 | 0.0741 | 36 | 46 | 8 | 20 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 82 | 0.0711 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05112 | 0.0447 |
| Etoposide | 180614_BG_03 | 919 | 0.0969 | 51 | 43 | 6 | 8 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 94 | 0.0928 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07280 | 0.0078 |
| Etoposide | 180614_BG_03 | 986 | 0.1017 | 86 | 23 | 14 | 4 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 109 | 0.0995 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07955 | 0.0246 |
| Etoposide | 180614_BG_03 | 1042 | 0.1357 | 100 | 55 | 14 | 17 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 155 | 0.1295 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10949 | 0.0380 |
| Etoposide | 180614_BG_04 | 1122 | 0.1804 | 186 | 50 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 236 | 0.1738 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.15379 | 0.0561 |
| Etoposide | 180614_BG_04 | 1036 | 0.1737 | 173 | 37 | 8 | 10 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 210 | 0.1685 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.14854 | 0.0366 |
| Etoposide | 180614_BG_04 | 1143 | 0.1317 | 102 | 62 | 12 | 4 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_9 | 164 | 0.1255 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10548 | 0.0608 |
| Etoposide | 180614_BG_02 | 1013 | 0.0862 | 54 | 38 | 4 | 15 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 92 | 0.0833 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06326 | 0.0311 |
| Etoposide | 180614_BG_02 | 888 | 0.0722 | 26 | 40 | 6 | 22 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 66 | 0.0692 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04919 | -0.0003 |
| Etoposide | 180614_BG_02 | 1004 | 0.0740 | 37 | 40 | 10 | 7 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 77 | 0.0712 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05123 | 0.0290 |
| Etoposide | 180614_BG_03 | 955 | 0.1212 | 85 | 41 | 4 | 13 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 126 | 0.1166 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.09656 | 0.0170 |
| Etoposide | 180614_BG_03 | 933 | 0.1292 | 81 | 50 | 7 | 17 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 131 | 0.1231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10312 | 0.0114 |
| Etoposide | 180614_BG_03 | 1029 | 0.0982 | 61 | 46 | 14 | 16 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 107 | 0.0942 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07419 | 0.0349 |
| Etoposide | 180614_BG_04 | 1173 | 0.1443 | 95 | 88 | 9 | 8 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 183 | 0.1350 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.11496 | 0.0672 |
| Etoposide | 180614_BG_04 | 1069 | 0.2223 | 213 | 72 | 13 | 7 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 285 | 0.2105 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.19049 | 0.0442 |
| Etoposide | 180614_BG_04 | 1094 | 0.2332 | 227 | 81 | 13 | 12 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 308 | 0.2197 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.19969 | 0.0499 |
| Neratinib | 180614_BG_02 | 16786 | 0.0176 | 52 | 245 | 3 | 13 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_1 | 297 | 0.0174 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00261 | 0.9926 |
| Neratinib | 180614_BG_02 | 16959 | 0.0186 | 31 | 285 | 8 | 22 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_2 | 316 | 0.0183 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00170 | 0.9974 |
| Neratinib | 180614_BG_02 | 17386 | 0.0184 | 20 | 300 | 11 | 17 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_3 | 320 | 0.0181 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00192 | 1.0091 |
| Neratinib | 180614_BG_03 | 17573 | 0.0218 | 100 | 286 | 3 | 17 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_4 | 386 | 0.0215 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00150 | 1.0141 |
| Neratinib | 180614_BG_03 | 17016 | 0.0189 | 69 | 254 | 14 | 10 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_5 | 323 | 0.0186 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00137 | 0.9989 |
| Neratinib | 180614_BG_03 | 16626 | 0.0137 | 59 | 170 | 14 | 11 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_6 | 229 | 0.0136 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00641 | 0.9881 |
| Neratinib | 180614_BG_04 | 17399 | 0.0186 | 94 | 232 | 4 | 5 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_7 | 326 | 0.0184 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00160 | 1.0094 |
| Neratinib | 180614_BG_04 | 16725 | 0.0206 | 94 | 252 | 11 | 22 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_8 | 346 | 0.0203 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00027 | 0.9909 |
| Neratinib | 180614_BG_04 | 14330 | 0.0207 | 92 | 206 | 13 | 16 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_9 | 298 | 0.0204 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00038 | 0.9200 |