LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180703_BG_12 | 8484 | 0.0196 | 52 | 115 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 167 | 0.0193 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01249 | 0.5800 |
| Alpelisib | 180703_BG_12 | 7421 | 0.0235 | 57 | 119 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 176 | 0.0232 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00863 | 0.5275 |
| Dasatinib | 180703_BG_10 | 18073 | 0.0182 | 57 | 273 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 330 | 0.0179 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01387 | 0.9127 |
| Dasatinib | 180703_BG_10 | 20280 | 0.0158 | 43 | 278 | 10 | 17 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 321 | 0.0156 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01622 | 0.9692 |
| Dasatinib | 180703_BG_10 | 20272 | 0.0190 | 48 | 338 | 12 | 4 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 386 | 0.0187 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01311 | 0.9690 |
| Dasatinib | 180703_BG_11 | 20538 | 0.0229 | 95 | 378 | 10 | 17 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 473 | 0.0225 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00929 | 0.9755 |
| Dasatinib | 180703_BG_11 | 20318 | 0.0226 | 97 | 365 | 10 | 18 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 462 | 0.0222 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00957 | 0.9701 |
| Dasatinib | 180703_BG_11 | 20117 | 0.0266 | 121 | 418 | 13 | 18 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 539 | 0.0261 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00571 | 0.9652 |
| Dasatinib | 180703_BG_12 | 20044 | 0.0203 | 54 | 354 | 6 | 19 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 408 | 0.0199 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01185 | 0.9634 |
| Dasatinib | 180703_BG_12 | 20786 | 0.0298 | 71 | 550 | 9 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 621 | 0.0290 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00279 | 0.9815 |
| Dasatinib | 180703_BG_12 | 20310 | 0.0239 | 70 | 417 | 11 | 19 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 487 | 0.0234 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00838 | 0.9699 |
| Dasatinib | 180703_BG_10 | 19604 | 0.0179 | 63 | 290 | 9 | 14 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 353 | 0.0177 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01411 | 0.9524 |
| Dasatinib | 180703_BG_10 | 19342 | 0.0178 | 55 | 290 | 12 | 9 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 345 | 0.0175 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01427 | 0.9458 |
| Dasatinib | 180703_BG_10 | 19404 | 0.0256 | 96 | 403 | 13 | 3 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 499 | 0.0251 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00673 | 0.9473 |
| Dasatinib | 180703_BG_11 | 18968 | 0.0309 | 164 | 427 | 5 | 15 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 591 | 0.0302 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00158 | 0.9362 |
| Dasatinib | 180703_BG_11 | 20039 | 0.0221 | 128 | 318 | 8 | 20 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 446 | 0.0218 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01003 | 0.9633 |
| Dasatinib | 180703_BG_11 | 18400 | 0.0236 | 157 | 281 | 9 | 15 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 438 | 0.0233 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00855 | 0.9214 |
| Dasatinib | 180703_BG_12 | 20034 | 0.0252 | 91 | 416 | 7 | 12 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 507 | 0.0247 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00712 | 0.9631 |
| Dasatinib | 180703_BG_12 | 19651 | 0.0203 | 59 | 341 | 9 | 10 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 400 | 0.0199 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01185 | 0.9536 |
| Dasatinib | 180703_BG_12 | 20973 | 0.0244 | 65 | 449 | 9 | 11 | Dasatinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 514 | 0.0239 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00788 | 0.9860 |
| Dasatinib | 180703_BG_10 | 17973 | 0.0186 | 67 | 269 | 8 | 21 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_1 | 336 | 0.0184 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01345 | 0.9100 |
| Dasatinib | 180703_BG_10 | 17271 | 0.0152 | 49 | 214 | 11 | 16 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 263 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.8909 |
| Dasatinib | 180703_BG_10 | 18337 | 0.0142 | 51 | 210 | 12 | 18 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 261 | 0.0140 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01777 | 0.9197 |
| Dasatinib | 180703_BG_11 | 16833 | 0.0268 | 169 | 286 | 3 | 7 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_4 | 455 | 0.0263 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00548 | 0.8787 |
| Dasatinib | 180703_BG_11 | 17194 | 0.0183 | 107 | 209 | 6 | 15 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 316 | 0.0180 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01375 | 0.8888 |