LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180703_BG_10 | 14304 | 0.0180 | 62 | 196 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_1 | 258 | 0.0177 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01408 | 0.8029 |
| Alpelisib | 180703_BG_10 | 14480 | 0.0173 | 76 | 176 | 6 | 5 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_2 | 252 | 0.0171 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01469 | 0.8085 |
| Alpelisib | 180703_BG_10 | 14895 | 0.0138 | 47 | 159 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 206 | 0.0136 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01816 | 0.8215 |
| Alpelisib | 180703_BG_11 | 15285 | 0.0196 | 106 | 195 | 4 | 9 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_4 | 301 | 0.0193 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01249 | 0.8334 |
| Alpelisib | 180703_BG_11 | 15154 | 0.0278 | 207 | 220 | 5 | 13 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_5 | 427 | 0.0274 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00439 | 0.8294 |
| Alpelisib | 180703_BG_11 | 14297 | 0.0233 | 136 | 201 | 11 | 6 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_6 | 337 | 0.0230 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00877 | 0.8027 |
| Alpelisib | 180703_BG_12 | 13199 | 0.0158 | 49 | 160 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 209 | 0.0156 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01621 | 0.7667 |
| Alpelisib | 180703_BG_12 | 15689 | 0.0186 | 94 | 199 | 5 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 293 | 0.0183 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01347 | 0.8455 |
| Alpelisib | 180703_BG_12 | 14515 | 0.0206 | 90 | 211 | 7 | 18 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 301 | 0.0203 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01148 | 0.8096 |
| Alpelisib | 180703_BG_10 | 11523 | 0.0180 | 64 | 145 | 6 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 209 | 0.0178 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01398 | 0.7071 |
| Alpelisib | 180703_BG_10 | 10077 | 0.0135 | 44 | 93 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 137 | 0.0134 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01839 | 0.6502 |
| Alpelisib | 180703_BG_10 | 11828 | 0.0168 | 39 | 160 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 199 | 0.0165 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01525 | 0.7184 |
| Alpelisib | 180703_BG_11 | 11626 | 0.0249 | 123 | 170 | 8 | 4 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 293 | 0.0246 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00722 | 0.7109 |
| Alpelisib | 180703_BG_11 | 12303 | 0.0218 | 109 | 161 | 10 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 270 | 0.0215 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01032 | 0.7356 |
| Alpelisib | 180703_BG_11 | 12619 | 0.0242 | 138 | 171 | 11 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 309 | 0.0239 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00790 | 0.7467 |
| Alpelisib | 180703_BG_12 | 11804 | 0.0241 | 86 | 201 | 5 | 19 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 287 | 0.0237 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00806 | 0.7175 |
| Alpelisib | 180703_BG_12 | 12063 | 0.0162 | 30 | 166 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 196 | 0.0160 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01581 | 0.7270 |
| Alpelisib | 180703_BG_12 | 11660 | 0.0184 | 68 | 148 | 14 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 216 | 0.0182 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01361 | 0.7122 |
| Alpelisib | 180703_BG_10 | 8407 | 0.0152 | 39 | 89 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 128 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.5764 |
| Alpelisib | 180703_BG_10 | 7863 | 0.0202 | 62 | 98 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 160 | 0.0199 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01186 | 0.5500 |
| Alpelisib | 180703_BG_10 | 7647 | 0.0137 | 32 | 73 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 105 | 0.0135 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01825 | 0.5391 |
| Alpelisib | 180703_BG_11 | 8777 | 0.0426 | 221 | 162 | 3 | 11 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_4 | 383 | 0.0418 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01001 | 0.5936 |
| Alpelisib | 180703_BG_11 | 7291 | 0.0268 | 100 | 98 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_5 | 198 | 0.0264 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00536 | 0.5207 |
| Alpelisib | 180703_BG_11 | 7710 | 0.0342 | 129 | 139 | 6 | 16 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_6 | 268 | 0.0336 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00179 | 0.5423 |
| Alpelisib | 180703_BG_12 | 8407 | 0.0239 | 70 | 133 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 203 | 0.0236 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00822 | 0.5764 |