LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180614_BG_03 | 1799 | 0.0298 | 14 | 40 | 9 | 22 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_6 | 54 | 0.0291 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00915 | 0.1799 |
| Trametinib | 180614_BG_04 | 1778 | 0.0717 | 90 | 44 | 6 | 20 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_7 | 134 | 0.0701 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05009 | 0.1766 |
| Trametinib | 180614_BG_04 | 2092 | 0.0702 | 73 | 79 | 13 | 4 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_8 | 152 | 0.0677 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04774 | 0.2224 |
| Trametinib | 180614_BG_04 | 2098 | 0.0827 | 150 | 36 | 14 | 7 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_9 | 186 | 0.0814 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06144 | 0.2232 |
| Vorinostat | 180614_BG_02 | 17518 | 0.0216 | 51 | 328 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 379 | 0.0212 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00118 | 1.0126 |
| Vorinostat | 180614_BG_02 | 16445 | 0.0225 | 47 | 324 | 6 | 11 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 371 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00207 | 0.9830 |
| Vorinostat | 180614_BG_02 | 16719 | 0.0215 | 51 | 310 | 8 | 10 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 361 | 0.0211 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00114 | 0.9907 |
| Vorinostat | 180614_BG_03 | 16891 | 0.0244 | 97 | 318 | 7 | 7 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 415 | 0.0240 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00398 | 0.9955 |
| Vorinostat | 180614_BG_03 | 16681 | 0.0177 | 44 | 252 | 8 | 22 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 296 | 0.0174 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00256 | 0.9896 |
| Vorinostat | 180614_BG_03 | 17415 | 0.0189 | 54 | 277 | 9 | 3 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 331 | 0.0187 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00134 | 1.0098 |
| Vorinostat | 180614_BG_04 | 16463 | 0.0238 | 146 | 250 | 5 | 21 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 396 | 0.0235 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00349 | 0.9835 |
| Vorinostat | 180614_BG_04 | 16612 | 0.0279 | 164 | 304 | 8 | 12 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 468 | 0.0274 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00740 | 0.9877 |
| Vorinostat | 180614_BG_04 | 16418 | 0.0235 | 129 | 260 | 12 | 18 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 389 | 0.0231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00315 | 0.9822 |
| Vorinostat | 180614_BG_02 | 17253 | 0.0200 | 54 | 292 | 8 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 346 | 0.0197 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00034 | 1.0054 |
| Vorinostat | 180614_BG_02 | 16681 | 0.0158 | 17 | 246 | 13 | 17 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 263 | 0.0155 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00447 | 0.9896 |
| Vorinostat | 180614_BG_02 | 17718 | 0.0187 | 25 | 306 | 13 | 19 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 331 | 0.0183 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00166 | 1.0180 |
| Vorinostat | 180614_BG_03 | 16655 | 0.0254 | 112 | 314 | 7 | 6 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 426 | 0.0249 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00494 | 0.9889 |
| Vorinostat | 180614_BG_03 | 16380 | 0.0232 | 97 | 285 | 7 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 382 | 0.0228 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00279 | 0.9812 |
| Vorinostat | 180614_BG_03 | 16950 | 0.0227 | 93 | 294 | 11 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 387 | 0.0223 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00233 | 0.9971 |
| Vorinostat | 180614_BG_04 | 14306 | 0.0229 | 143 | 188 | 3 | 18 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 331 | 0.0226 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00262 | 0.9192 |
| Vorinostat | 180614_BG_04 | 16773 | 0.0196 | 91 | 239 | 5 | 22 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 330 | 0.0193 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00070 | 0.9922 |
| Vorinostat | 180614_BG_04 | 17329 | 0.0183 | 81 | 237 | 10 | 19 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 318 | 0.0180 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00198 | 1.0075 |
| Vorinostat | 180614_BG_02 | 17491 | 0.0215 | 54 | 323 | 6 | 19 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 377 | 0.0211 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00110 | 1.0119 |
| Vorinostat | 180614_BG_02 | 16197 | 0.0181 | 26 | 267 | 8 | 18 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 293 | 0.0178 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00223 | 0.9759 |
| Vorinostat | 180614_BG_02 | 16093 | 0.0208 | 61 | 275 | 14 | 6 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 336 | 0.0205 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00046 | 0.9730 |