LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180614_BG_04 | 2091 | 0.0519 | 85 | 28 | 10 | 5 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_8 | 113 | 0.0513 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03127 | 0.2223 |
| Trametinib | 180614_BG_04 | 1907 | 0.0967 | 151 | 48 | 11 | 10 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_9 | 199 | 0.0945 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07450 | 0.1961 |
| Trametinib | 180614_BG_02 | 1685 | 0.0366 | 35 | 28 | 4 | 17 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_1 | 63 | 0.0360 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01605 | 0.1619 |
| Trametinib | 180614_BG_02 | 2043 | 0.0400 | 57 | 27 | 8 | 13 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_2 | 84 | 0.0395 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01950 | 0.2156 |
| Trametinib | 180614_BG_02 | 1846 | 0.0413 | 42 | 36 | 11 | 10 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_3 | 78 | 0.0405 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02055 | 0.1870 |
| Trametinib | 180614_BG_03 | 1792 | 0.0301 | 36 | 19 | 4 | 22 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_4 | 55 | 0.0298 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00978 | 0.1788 |
| Trametinib | 180614_BG_03 | 2070 | 0.0505 | 70 | 38 | 8 | 12 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_5 | 108 | 0.0496 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02959 | 0.2194 |
| Trametinib | 180614_BG_03 | 1942 | 0.0529 | 79 | 28 | 14 | 7 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 107 | 0.0522 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03223 | 0.2012 |
| Trametinib | 180614_BG_04 | 2035 | 0.0794 | 130 | 42 | 6 | 13 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_7 | 172 | 0.0779 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05794 | 0.2145 |
| Trametinib | 180614_BG_04 | 1952 | 0.0806 | 119 | 48 | 8 | 9 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_8 | 167 | 0.0788 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05882 | 0.2027 |
| Trametinib | 180614_BG_04 | 1969 | 0.0613 | 86 | 40 | 10 | 21 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_9 | 126 | 0.0601 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04015 | 0.2051 |
| Trametinib | 180614_BG_02 | 1775 | 0.0252 | 11 | 34 | 3 | 20 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_1 | 45 | 0.0247 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00473 | 0.1762 |
| Trametinib | 180614_BG_02 | 1835 | 0.0469 | 42 | 46 | 4 | 3 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_2 | 88 | 0.0458 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02577 | 0.1854 |
| Trametinib | 180614_BG_02 | 1913 | 0.0438 | 51 | 35 | 8 | 5 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_3 | 86 | 0.0430 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02303 | 0.1970 |
| Trametinib | 180614_BG_03 | 1901 | 0.0397 | 40 | 37 | 6 | 22 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_4 | 77 | 0.0389 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01893 | 0.1952 |
| Trametinib | 180614_BG_03 | 1784 | 0.0643 | 81 | 39 | 7 | 10 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_5 | 120 | 0.0630 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04303 | 0.1776 |
| Trametinib | 180614_BG_03 | 1982 | 0.0360 | 47 | 26 | 10 | 19 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_6 | 73 | 0.0355 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01553 | 0.2070 |
| Trametinib | 180614_BG_04 | 1943 | 0.0585 | 75 | 43 | 8 | 3 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_7 | 118 | 0.0573 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03726 | 0.2014 |
| Trametinib | 180614_BG_04 | 1649 | 0.0690 | 91 | 29 | 8 | 13 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_8 | 120 | 0.0678 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04784 | 0.1560 |
| Trametinib | 180614_BG_04 | 2245 | 0.0642 | 108 | 43 | 11 | 8 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_9 | 151 | 0.0630 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04303 | 0.2428 |
| Trametinib | 180614_BG_02 | 1792 | 0.0319 | 27 | 31 | 8 | 16 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_1 | 58 | 0.0314 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01136 | 0.1788 |
| Trametinib | 180614_BG_02 | 1751 | 0.0322 | 18 | 39 | 9 | 11 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_2 | 57 | 0.0315 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01153 | 0.1724 |
| Trametinib | 180614_BG_02 | 1951 | 0.0255 | 6 | 44 | 9 | 21 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_3 | 50 | 0.0250 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00499 | 0.2025 |
| Trametinib | 180614_BG_03 | 1896 | 0.0327 | 32 | 31 | 8 | 10 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_4 | 63 | 0.0322 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01216 | 0.1945 |
| Trametinib | 180614_BG_03 | 1491 | 0.0576 | 55 | 34 | 8 | 21 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_5 | 89 | 0.0563 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03633 | 0.1290 |