LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset - HMS LINCS Database

LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)

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Small Molecule	barcode	cell_count	frac_dead	corpse_count	cell_count_dead	row	column	agent	concentration	role	timepoint	replicate	cell_line	dead_count	fraction_dead	cell_count__time0	dead_count__time0	cell_count__ctrl	dead_count__ctrl	fraction_dead__ctrl	increase_fraction_dead	GRvalue
Trametinib	180619_MC_11	851	0.1015	65	28	8	21	Trametinib	0.998	treatment	72	2	MCF10A-GM_5	93	0.0985	635.9	71.1	15071	356.7	0.0231	0.07544	0.0659
Trametinib	180619_MC_11	1041	0.1120	84	42	9	22	Trametinib	0.998	treatment	72	2	MCF10A-GM_6	126	0.1080	635.9	71.1	15071	356.7	0.0231	0.08489	0.1140
Trametinib	180619_MC_12	979	0.1497	110	53	6	20	Trametinib	0.998	treatment	72	2	MCF10A-GM_7	163	0.1427	635.9	71.1	15071	356.7	0.0231	0.11966	0.0991
Trametinib	180619_MC_12	953	0.2075	136	90	13	4	Trametinib	0.998	treatment	72	2	MCF10A-GM_8	226	0.1917	635.9	71.1	15071	356.7	0.0231	0.16861	0.0926
Trametinib	180619_MC_12	1015	0.1123	89	35	14	7	Trametinib	0.998	treatment	72	2	MCF10A-GM_9	124	0.1089	635.9	71.1	15071	356.7	0.0231	0.08579	0.1078
Vorinostat	180619_MC_10	15087	0.0204	61	248	5	13	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_1	309	0.0201	635.9	71.1	15071	356.7	0.0231	-0.00300	1.0005
Vorinostat	180619_MC_10	15179	0.0219	41	293	6	11	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_2	334	0.0215	635.9	71.1	15071	356.7	0.0231	-0.00154	1.0031
Vorinostat	180619_MC_10	15536	0.0223	59	288	8	10	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_3	347	0.0218	635.9	71.1	15071	356.7	0.0231	-0.00123	1.0133
Vorinostat	180619_MC_11	14282	0.0251	87	274	7	7	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_4	361	0.0247	635.9	71.1	15071	356.7	0.0231	0.00158	0.9766
Vorinostat	180619_MC_11	14369	0.0208	71	229	8	22	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_5	300	0.0205	635.9	71.1	15071	356.7	0.0231	-0.00262	0.9792
Vorinostat	180619_MC_11	14134	0.0242	77	267	9	3	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_6	344	0.0238	635.9	71.1	15071	356.7	0.0231	0.00069	0.9721
Vorinostat	180619_MC_12	15695	0.0218	94	250	5	21	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_7	344	0.0214	635.9	71.1	15071	356.7	0.0231	-0.00163	1.0178
Vorinostat	180619_MC_12	15667	0.0215	96	243	8	12	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_8	339	0.0212	635.9	71.1	15071	356.7	0.0231	-0.00189	1.0171
Vorinostat	180619_MC_12	15151	0.0216	68	260	12	18	Vorinostat	0.003326667	treatment	72	2	MCF10A-GM_9	328	0.0212	635.9	71.1	15071	356.7	0.0231	-0.00188	1.0023
Vorinostat	180619_MC_10	15234	0.0205	50	264	8	12	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_1	314	0.0202	635.9	71.1	15071	356.7	0.0231	-0.00288	1.0047
Vorinostat	180619_MC_10	14436	0.0169	22	222	13	17	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_2	244	0.0166	635.9	71.1	15071	356.7	0.0231	-0.00645	0.9812
Vorinostat	180619_MC_10	14504	0.0199	47	242	13	19	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_3	289	0.0195	635.9	71.1	15071	356.7	0.0231	-0.00354	0.9833
Vorinostat	180619_MC_11	14452	0.0249	74	287	7	6	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_4	361	0.0244	635.9	71.1	15071	356.7	0.0231	0.00130	0.9817
Vorinostat	180619_MC_11	15129	0.0267	95	312	7	12	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_5	407	0.0262	635.9	71.1	15071	356.7	0.0231	0.00312	1.0017
Vorinostat	180619_MC_11	15050	0.0204	41	267	11	12	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_6	308	0.0201	635.9	71.1	15071	356.7	0.0231	-0.00302	0.9994
Vorinostat	180619_MC_12	15345	0.0259	115	286	3	18	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_7	401	0.0255	635.9	71.1	15071	356.7	0.0231	0.00239	1.0079
Vorinostat	180619_MC_12	15769	0.0229	92	271	5	22	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_8	363	0.0225	635.9	71.1	15071	356.7	0.0231	-0.00057	1.0199
Vorinostat	180619_MC_12	15170	0.0252	98	287	10	19	Vorinostat	0.00998	treatment	72	2	MCF10A-GM_9	385	0.0248	635.9	71.1	15071	356.7	0.0231	0.00168	1.0029
Vorinostat	180619_MC_10	14448	0.0224	47	278	6	19	Vorinostat	0.033266667	treatment	72	2	MCF10A-GM_1	325	0.0220	635.9	71.1	15071	356.7	0.0231	-0.00107	0.9816
Vorinostat	180619_MC_10	15024	0.0232	66	284	8	18	Vorinostat	0.033266667	treatment	72	2	MCF10A-GM_2	350	0.0228	635.9	71.1	15071	356.7	0.0231	-0.00031	0.9986

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HMS LINCS Project

LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)