LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180615_MC_07 | 3002 | 0.0405 | 61 | 63 | 14 | 13 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_6 | 124 | 0.0397 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01627 | 0.4487 |
| Neratinib | 180615_MC_08 | 4230 | 0.0347 | 69 | 80 | 6 | 10 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_7 | 149 | 0.0340 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01063 | 0.5660 |
| Neratinib | 180615_MC_08 | 3116 | 0.0240 | 3 | 72 | 7 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_8 | 75 | 0.0235 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00011 | 0.4610 |
| Neratinib | 180615_MC_08 | 4034 | 0.0400 | 64 | 100 | 7 | 7 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_9 | 164 | 0.0391 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01567 | 0.5492 |
| Neratinib | 180615_MC_06 | 1052 | 0.0822 | 43 | 47 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_1 | 90 | 0.0788 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.05541 | 0.1419 |
| Neratinib | 180615_MC_06 | 1053 | 0.0729 | 17 | 61 | 5 | 19 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_2 | 78 | 0.0690 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04557 | 0.1422 |
| Neratinib | 180615_MC_06 | 1060 | 0.0621 | 19 | 48 | 9 | 9 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_3 | 67 | 0.0594 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03605 | 0.1439 |
| Neratinib | 180615_MC_07 | 1895 | 0.0381 | 19 | 54 | 5 | 12 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_4 | 73 | 0.0371 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01370 | 0.3051 |
| Neratinib | 180615_MC_07 | 1278 | 0.0622 | 40 | 42 | 8 | 19 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_5 | 82 | 0.0603 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03690 | 0.1935 |
| Neratinib | 180615_MC_07 | 1202 | 0.0529 | 26 | 39 | 9 | 20 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_6 | 65 | 0.0513 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.02790 | 0.1770 |
| Neratinib | 180615_MC_08 | 2266 | 0.0556 | 74 | 56 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_7 | 130 | 0.0543 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03086 | 0.3591 |
| Neratinib | 180615_MC_08 | 1919 | 0.0608 | 56 | 64 | 8 | 14 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_8 | 120 | 0.0589 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03545 | 0.3088 |
| Neratinib | 180615_MC_08 | 1720 | 0.0500 | 41 | 47 | 13 | 14 | Neratinib | 3.160329364 | treatment | 72 | 1 | MCF10A-GM_9 | 88 | 0.0487 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.02527 | 0.2767 |
| Taxol | 180615_MC_06 | 12699 | 0.0243 | 42 | 267 | 7 | 15 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_1 | 309 | 0.0238 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00036 | 1.0098 |
| Taxol | 180615_MC_06 | 13077 | 0.0191 | 24 | 226 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_2 | 250 | 0.0188 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00464 | 1.0232 |
| Taxol | 180615_MC_06 | 12066 | 0.0220 | 14 | 252 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_3 | 266 | 0.0216 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00183 | 0.9866 |
| Taxol | 180615_MC_07 | 11591 | 0.0263 | 51 | 255 | 6 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_4 | 306 | 0.0257 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00232 | 0.9686 |
| Taxol | 180615_MC_07 | 13191 | 0.0236 | 57 | 256 | 8 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_5 | 313 | 0.0232 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00022 | 1.0272 |
| Taxol | 180615_MC_07 | 11983 | 0.0181 | 11 | 206 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_6 | 217 | 0.0178 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00561 | 0.9835 |
| Taxol | 180615_MC_08 | 12110 | 0.0226 | 41 | 234 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_7 | 275 | 0.0222 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00119 | 0.9882 |
| Taxol | 180615_MC_08 | 12213 | 0.0316 | 88 | 301 | 10 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_8 | 389 | 0.0309 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00747 | 0.9921 |
| Taxol | 180615_MC_08 | 13261 | 0.0214 | 33 | 252 | 13 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_9 | 285 | 0.0210 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00236 | 1.0296 |
| Taxol | 180615_MC_06 | 11162 | 0.0326 | 50 | 316 | 3 | 16 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_1 | 366 | 0.0317 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00835 | 0.9518 |
| Taxol | 180615_MC_06 | 10552 | 0.0236 | 25 | 225 | 12 | 7 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_2 | 250 | 0.0231 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00025 | 0.9271 |
| Taxol | 180615_MC_06 | 10899 | 0.0252 | 28 | 247 | 14 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_3 | 275 | 0.0246 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00121 | 0.9413 |