LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180615_MC_07 | 11295 | 0.0207 | 85 | 150 | 4 | 4 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_4 | 235 | 0.0204 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00302 | 0.9570 |
| Vorinostat | 180615_MC_07 | 13534 | 0.0234 | 27 | 290 | 7 | 8 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 317 | 0.0229 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00051 | 1.0390 |
| Vorinostat | 180615_MC_07 | 12088 | 0.0178 | 53 | 163 | 9 | 21 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 216 | 0.0176 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00584 | 0.9874 |
| Vorinostat | 180615_MC_08 | 11486 | 0.0262 | 57 | 246 | 5 | 12 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_7 | 303 | 0.0257 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00230 | 0.9645 |
| Vorinostat | 180615_MC_08 | 10875 | 0.0256 | 50 | 230 | 7 | 17 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_8 | 280 | 0.0251 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00170 | 0.9403 |
| Vorinostat | 180615_MC_08 | 12675 | 0.0268 | 45 | 296 | 13 | 18 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_9 | 341 | 0.0262 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00280 | 1.0089 |
| Vorinostat | 180615_MC_06 | 9760 | 0.0282 | 82 | 196 | 4 | 8 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_1 | 278 | 0.0277 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00430 | 0.8932 |
| Vorinostat | 180615_MC_06 | 10845 | 0.0251 | 58 | 216 | 10 | 10 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 274 | 0.0246 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00124 | 0.9391 |
| Vorinostat | 180615_MC_06 | 11113 | 0.0217 | 18 | 224 | 13 | 11 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_3 | 242 | 0.0213 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00209 | 0.9498 |
| Vorinostat | 180615_MC_07 | 11700 | 0.0222 | 78 | 184 | 4 | 14 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_4 | 262 | 0.0219 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00150 | 0.9728 |
| Vorinostat | 180615_MC_07 | 11440 | 0.0201 | 32 | 199 | 9 | 18 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_5 | 231 | 0.0198 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00361 | 0.9627 |
| Vorinostat | 180615_MC_07 | 10559 | 0.0164 | 60 | 114 | 10 | 15 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_6 | 174 | 0.0162 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00719 | 0.9273 |
| Vorinostat | 180615_MC_08 | 11418 | 0.0255 | 90 | 204 | 3 | 16 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_7 | 294 | 0.0251 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00170 | 0.9619 |
| Vorinostat | 180615_MC_08 | 10699 | 0.0218 | 37 | 197 | 5 | 9 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 234 | 0.0214 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00200 | 0.9331 |
| Vorinostat | 180615_MC_08 | 11683 | 0.0276 | 73 | 252 | 10 | 6 | Vorinostat | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_9 | 325 | 0.0271 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00367 | 0.9721 |
| Vorinostat | 180615_MC_06 | 7985 | 0.0236 | 24 | 165 | 6 | 21 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_1 | 189 | 0.0231 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00028 | 0.8089 |
| Vorinostat | 180615_MC_06 | 8554 | 0.0161 | 19 | 119 | 7 | 9 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_2 | 138 | 0.0159 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00752 | 0.8374 |
| Vorinostat | 180615_MC_06 | 8467 | 0.0209 | 17 | 160 | 13 | 16 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_3 | 177 | 0.0205 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00292 | 0.8331 |
| Vorinostat | 180615_MC_07 | 8755 | 0.0182 | 32 | 128 | 3 | 5 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 160 | 0.0179 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00545 | 0.8471 |
| Vorinostat | 180615_MC_07 | 9335 | 0.0234 | 61 | 159 | 10 | 7 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_5 | 220 | 0.0230 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00037 | 0.8742 |
| Vorinostat | 180615_MC_07 | 8284 | 0.0164 | 21 | 115 | 11 | 3 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_6 | 136 | 0.0162 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00725 | 0.8241 |
| Vorinostat | 180615_MC_08 | 8731 | 0.0270 | 33 | 204 | 3 | 4 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_7 | 237 | 0.0264 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00303 | 0.8460 |
| Vorinostat | 180615_MC_08 | 8057 | 0.0299 | 78 | 165 | 6 | 15 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_8 | 243 | 0.0293 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00588 | 0.8126 |
| Vorinostat | 180615_MC_08 | 8307 | 0.0279 | 74 | 160 | 12 | 15 | Vorinostat | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_9 | 234 | 0.0274 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00400 | 0.8252 |
| Vorinostat | 180615_MC_06 | 4778 | 0.0206 | 24 | 75 | 5 | 5 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 99 | 0.0203 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00310 | 0.6099 |