LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dasatinib | 180615_MC_08 | 1905 | 0.0644 | 35 | 90 | 12 | 11 | Dasatinib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_9 | 125 | 0.0616 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03818 | 0.3067 |
| Dasatinib | 180615_MC_06 | 622 | 0.2146 | 21 | 117 | 7 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_1 | 138 | 0.1816 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.15818 | 0.0135 |
| Dasatinib | 180615_MC_06 | 1030 | 0.1077 | 10 | 102 | 12 | 3 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 112 | 0.0981 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07468 | 0.1364 |
| Dasatinib | 180615_MC_06 | 1073 | 0.1348 | 10 | 136 | 13 | 9 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 146 | 0.1198 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09637 | 0.1470 |
| Dasatinib | 180615_MC_07 | 1036 | 0.1653 | 41 | 137 | 12 | 8 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 178 | 0.1466 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.12322 | 0.1379 |
| Dasatinib | 180615_MC_07 | 976 | 0.1235 | 12 | 110 | 13 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 122 | 0.1111 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08771 | 0.1226 |
| Dasatinib | 180615_MC_07 | 853 | 0.1176 | 14 | 88 | 13 | 22 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 102 | 0.1068 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08341 | 0.0888 |
| Dasatinib | 180615_MC_08 | 940 | 0.1772 | 53 | 123 | 3 | 13 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 176 | 0.1577 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.13431 | 0.1131 |
| Dasatinib | 180615_MC_08 | 981 | 0.2222 | 90 | 148 | 4 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 238 | 0.1952 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.17184 | 0.1239 |
| Dasatinib | 180615_MC_08 | 1039 | 0.1681 | 44 | 138 | 11 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_9 | 182 | 0.1491 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.12566 | 0.1387 |
| Dasatinib | 180615_MC_06 | 316 | 0.7741 | 47 | 234 | 4 | 13 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 281 | 0.4707 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.44729 | -0.1309 |
| Dasatinib | 180615_MC_06 | 310 | 0.7275 | 68 | 207 | 7 | 11 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 275 | 0.4701 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.44669 | -0.1346 |
| Dasatinib | 180615_MC_06 | 224 | 0.8833 | 33 | 194 | 8 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 227 | 0.5033 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.47993 | -0.1962 |
| Dasatinib | 180615_MC_07 | 300 | 0.7570 | 91 | 205 | 6 | 4 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 296 | 0.4966 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.47325 | -0.1411 |
| Dasatinib | 180615_MC_07 | 229 | 0.8161 | 32 | 181 | 7 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 213 | 0.4819 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.45850 | -0.1921 |
| Dasatinib | 180615_MC_07 | 271 | 0.8485 | 59 | 221 | 12 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 280 | 0.5082 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.48477 | -0.1607 |
| Dasatinib | 180615_MC_08 | 325 | 0.6322 | 42 | 190 | 5 | 8 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 232 | 0.4165 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.39312 | -0.1253 |
| Dasatinib | 180615_MC_08 | 285 | 0.7814 | 81 | 205 | 7 | 16 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 286 | 0.5009 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.47748 | -0.1510 |
| Dasatinib | 180615_MC_08 | 320 | 0.7718 | 70 | 231 | 11 | 16 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 301 | 0.4847 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.46130 | -0.1284 |
| Etoposide | 180615_MC_06 | 12855 | 0.0269 | 33 | 314 | 4 | 7 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 347 | 0.0263 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00289 | 1.0154 |
| Etoposide | 180615_MC_06 | 13348 | 0.0253 | 45 | 294 | 5 | 10 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 339 | 0.0248 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00137 | 1.0326 |
| Etoposide | 180615_MC_06 | 12330 | 0.0281 | 66 | 282 | 12 | 10 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 348 | 0.0274 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00405 | 0.9964 |
| Etoposide | 180615_MC_07 | 11418 | 0.0126 | 20 | 124 | 10 | 3 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 144 | 0.0125 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.01094 | 0.9619 |
| Etoposide | 180615_MC_07 | 11946 | 0.0183 | 58 | 162 | 10 | 20 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 220 | 0.0181 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00531 | 0.9821 |
| Etoposide | 180615_MC_07 | 12273 | 0.0239 | 72 | 223 | 12 | 18 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 295 | 0.0235 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00007 | 0.9943 |