LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180615_MC_07 | 911 | 0.0687 | 20 | 44 | 9 | 22 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_6 | 64 | 0.0656 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04224 | 0.1052 |
| Trametinib | 180615_MC_08 | 796 | 0.1612 | 85 | 57 | 6 | 20 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_7 | 142 | 0.1514 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.12799 | 0.0719 |
| Trametinib | 180615_MC_08 | 902 | 0.1390 | 19 | 109 | 13 | 4 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_8 | 128 | 0.1243 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.10087 | 0.1027 |
| Trametinib | 180615_MC_08 | 786 | 0.0683 | 19 | 36 | 14 | 7 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_9 | 55 | 0.0654 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04200 | 0.0688 |
| Vorinostat | 180615_MC_06 | 12341 | 0.0174 | 21 | 194 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 215 | 0.0171 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00627 | 0.9968 |
| Vorinostat | 180615_MC_06 | 11879 | 0.0235 | 27 | 253 | 6 | 11 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 280 | 0.0230 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00037 | 0.9796 |
| Vorinostat | 180615_MC_06 | 12792 | 0.0268 | 65 | 279 | 8 | 10 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 344 | 0.0262 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00279 | 1.0131 |
| Vorinostat | 180615_MC_07 | 12256 | 0.0208 | 35 | 221 | 7 | 7 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 256 | 0.0205 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00294 | 0.9937 |
| Vorinostat | 180615_MC_07 | 12107 | 0.0237 | 64 | 224 | 8 | 22 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 288 | 0.0232 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00016 | 0.9881 |
| Vorinostat | 180615_MC_07 | 13042 | 0.0134 | 17 | 158 | 9 | 3 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 175 | 0.0132 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.01016 | 1.0220 |
| Vorinostat | 180615_MC_08 | 12693 | 0.0240 | 34 | 271 | 5 | 21 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 305 | 0.0235 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00007 | 1.0096 |
| Vorinostat | 180615_MC_08 | 13879 | 0.0303 | 102 | 321 | 8 | 12 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 423 | 0.0296 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00618 | 1.0507 |
| Vorinostat | 180615_MC_08 | 11555 | 0.0265 | 67 | 241 | 12 | 18 | Vorinostat | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 308 | 0.0260 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00256 | 0.9672 |
| Vorinostat | 180615_MC_06 | 12381 | 0.0307 | 76 | 306 | 8 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 382 | 0.0299 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00653 | 0.9982 |
| Vorinostat | 180615_MC_06 | 11898 | 0.0211 | 23 | 229 | 13 | 17 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 252 | 0.0207 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00266 | 0.9803 |
| Vorinostat | 180615_MC_06 | 12552 | 0.0211 | 15 | 250 | 13 | 19 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 265 | 0.0207 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00272 | 1.0045 |
| Vorinostat | 180615_MC_07 | 12840 | 0.0179 | 32 | 199 | 7 | 6 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 231 | 0.0177 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00573 | 1.0148 |
| Vorinostat | 180615_MC_07 | 11698 | 0.0194 | 31 | 196 | 7 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 227 | 0.0190 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00436 | 0.9727 |
| Vorinostat | 180615_MC_07 | 12502 | 0.0242 | 27 | 276 | 11 | 12 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 303 | 0.0237 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00026 | 1.0027 |
| Vorinostat | 180615_MC_08 | 11434 | 0.0245 | 80 | 202 | 3 | 18 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 282 | 0.0241 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00067 | 0.9625 |
| Vorinostat | 180615_MC_08 | 12840 | 0.0231 | 42 | 255 | 5 | 22 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 297 | 0.0226 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00079 | 1.0148 |
| Vorinostat | 180615_MC_08 | 12257 | 0.0309 | 60 | 320 | 10 | 19 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 380 | 0.0301 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00667 | 0.9937 |
| Vorinostat | 180615_MC_06 | 11457 | 0.0251 | 36 | 253 | 6 | 19 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 289 | 0.0246 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00121 | 0.9634 |
| Vorinostat | 180615_MC_06 | 12648 | 0.0229 | 45 | 246 | 8 | 18 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 291 | 0.0225 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00091 | 1.0079 |
| Vorinostat | 180615_MC_06 | 10947 | 0.0255 | 54 | 227 | 14 | 6 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 281 | 0.0250 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00163 | 0.9432 |