Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
HCC1954 Ribociclib
66.3393103634
 0.5260 0.3269 43.1744 0.0265 0.1268 0.4412
0.000692485845485
CAL-120 SHP099
13.63352074
 0.7924 0.0042 16.9837 -1.0000 5.0000 0.4392
0.000724955
HCC1395 SHP099
inf
 0.5184 0.0927 5.0946 0.5377 5.0000 0.4367
0.000766633
SUM149PT Senexin B
inf
 0.5896 0.1339 0.0126 0.8101 1.1518 0.4355
0.000786678
HCC1395 Senexin B
6.42808065
 0.2209 0.2748 810.0166 -1.0000 0.2272 0.4287
0.000912711
HCC1937 GSK2334470
21.07472865
 0.5809 0.1504 509.5331 -1.0000 0.3449 0.4204
0.00109344
MDA-MB-436 LY3023414
4.691952741
 0.1749 0.3897 1000.0000 -0.3698 0.1033 0.4098
0.001372738
HME1 Senexin B
inf
 0.7841 0.1891 0.0158 0.7123 0.2814 0.4068
0.001463753
SUM1315MO2 AZD2014
0.001390649
 0.0852 0.6690 6.8904 -0.6708 0.1000 0.3997
0.001697935
HCC1143 SHP099
1449.842823
 0.7869 0.0529 1000.0000 0.0556 0.3172 0.3933
0.001935462
SK-BR-3 GSK2334470
inf
 0.1727 0.3229 0.0048 0.6054 5.0000 0.3843
0.002330067
MCF 10A Rucaparib
inf
 0.8695 0.0527 79.7513 0.7576 0.2151 0.3749
0.002812424
BT-20 GSK2334470
13.6041849907
 0.6953 0.0817 27.5398 -0.9501 1.5098 0.3727
0.00293794501251
HME1 Rucaparib
inf
 0.7189 0.1295 1000.0000 0.4363 0.1448 0.3705
0.003075156
HCC1954 GSK2334470
326.758853563
 0.7193 0.0862 1000.0000 -0.2160 0.3210 0.3690
0.00316182428427
HCC1428 LY3023414
4.66e-07
 -0.7374 1.2208 0.0032 -1.0000 0.1242 0.3630
0.003559188
SUM159PT Rucaparib
1.81722e+11
 0.7797 0.0896 999.9789 0.4809 0.1718 0.3608
0.003721786
HCC1428 RO-3306
3.430055795
 -0.4441 0.0143 3.8909 -0.2512 3.2292 0.3585
0.003891828
HCC38 Rucaparib
3274.321387
 0.6293 0.1296 1000.0000 0.1004 0.1890 0.3579
0.003936714
HCC1395 GSK2334470
54.2680197
 0.4791 0.2112 918.5477 -0.4410 0.2235 0.3535
0.004287213
HCC1806 AZD5363
1097.05246074
 0.6869 0.0528 1000.0000 0.0138 0.3031 0.3511
0.00448557172627
MDA-MB-436 AZD5363
392.3177575
 0.6113 0.1390 65.2715 0.2186 0.3204 0.3405
0.005494124
HCC1428 BMS-265246
0.000203941
 -0.4531 0.9502 0.0775 -0.8101 0.1622 0.3392
0.00563904
MDA-MB-361 Rucaparib
inf
 0.1133 0.3149 0.0128 0.5095 5.0000 0.3359
0.005993375
MDA-MB-436 GSK2334470
26.4830237
 0.7307 0.0123 64.9192 -0.9964 1.2226 0.3331
0.006324926