Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
MCF 10A GSK2334470
15.0731115613
 0.8830 -0.0129 18.7770 -1.0000 5.0000 0.4636
0.000172093714918
SUM159PT Senexin B
inf
 0.9016 0.0793 0.0000 0.9165 0.0100 0.0000
0.292587245
BT-549 Ribociclib
inf
 0.9258 0.0097 0.0000 0.9885 0.0100 0.0000
0.489440623384
MDA-MB-231 SHP099
inf
 0.9470 -0.0146 0.0000 1.0000 0.0100 -0.0002
0.198394332856
CAL-85-1 Ribociclib
inf
 0.9479 0.1502 0.0000 0.8929 0.0100 0.0000
1.0
MDA-MB-436 Ribociclib
inf
 0.9493 -0.0090 0.0000 1.0000 0.0100 -0.0149
0.928505437
HCC1806 SHP099
inf
 0.9525 -0.0087 0.0000 1.0000 0.0100 -0.0671
0.950463130981
AU565 SHP099
inf
 0.9751 0.0242 0.0000 0.9633 0.0100 0.0000
1.0
HCC1937 Ribociclib
inf
 0.9905 -0.0141 0.0000 0.9898 0.0100 0.0000
1.0
HCC1500 AZD5363
-inf
 0.9937
SK-BR-3 SHP099
inf
 0.9987 0.0260 0.0000 0.9879 0.0100 0.0000
1.0
HCC1500 Ribociclib
inf
 1.0336 0.4512 0.0000 0.5131 0.0100 0.0000
1.0
HCC70 Ribociclib
inf
 1.0564 -0.0040 0.0000 1.0000 0.0100 -0.1699
1.0
HCC1500 Rucaparib
#NAME?
 1.0742 0.0000 0.1000 0.0100
MDA-MB-231 AZD5363
inf
 1.0802 -0.0194 0.0000 1.0000 0.0100 -0.2298
1.0
HCC70 Rucaparib
inf
 1.1144 -0.0414 0.0000 1.0000 0.0100 -0.1078
1.0
HCC1428 AZD5363
inf
 1.8797 -0.1143 0.0000 1.0000 0.0100 -0.2534
1.0
MDA-MB-436 AZD6738
-inf
Hs 578T BMS-265246
-inf