Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
MDA-MB-157 SHP099
inf
 0.4006 0.1685 0.0000 0.8456 0.0100 0.0000
0.25024823
AU565 SHP099
inf
 0.9751 0.0242 0.0000 0.9633 0.0100 0.0000
1.0
CAL-120 Senexin B
inf
 0.8437 0.1267 0.0000 0.8683 0.0100 0.0000
0.139800748
HCC1428 Senexin B
-inf
 -0.2008 0.6803 0.0000 0.2756 0.0100 0.0000
0.123657155
CAL-85-1 AZD5363
inf
 0.2770 0.1987 0.0000 0.8552 0.0100 0.0000
0.179970694
HCC1937 SHP099
inf
 0.7745 0.0470 0.0000 0.9312 0.0100 0.0000
1.0
MDA-MB-468 Ribociclib
inf
 0.7972 0.0091 0.0000 0.9779 0.0100 0.0000
1.0
HCC1937 Ribociclib
inf
 0.9905 -0.0141 0.0000 0.9898 0.0100 0.0000
1.0
CAL-85-1 GSK2334470
inf
 0.1906 0.2483 0.0000 0.7764 0.0100 0.0000
0.11208861
CAL-85-1 Ribociclib
inf
 0.9479 0.1502 0.0000 0.8929 0.0100 0.0000
1.0
CAMA-1 SHP099
inf
 0.6544 0.0867 0.0000 0.9242 0.0100 0.0000
0.798838019
HCC1419 Rucaparib
inf
 0.8069 0.0539 0.0000 0.9485 0.0100 0.0000
0.337916631
HCC1500 Ribociclib
inf
 1.0336 0.4512 0.0000 0.5131 0.0100 0.0000
1.0
SK-BR-3 Senexin B
inf
 0.7921 0.1660 0.0000 0.8353 0.0100 0.0000
1.0
MDA-MB-134-VI Ribociclib
-inf
 0.2592 0.7185 0.0000 0.3047 0.0100 0.0000
0.311703691
CAMA-1 GSK2334470
inf
 0.6437 -0.0125 0.0000 0.9959 0.0100 0.0000
0.05607765
T47D Rucaparib
inf
 0.8130 0.0415 0.0000 0.9307 0.0100 0.0000
0.073451061
MDA-MB-361 SHP099
inf
 0.5804 0.1256 0.0000 0.8613 0.0100 0.0000
1.0
HCC1428 Ribociclib
#NAME?
 -0.3849 0.7838 0.0000 0.2963 0.0100 0.0000
0.210923138
CAL-85-1 SHP099
inf
 0.5820 0.2604 0.0000 0.8282 0.0100 0.0000
1.0
HCC1500 BMS-265246
-inf
 0.2444 0.9257 0.0000 0.1272 0.0100 0.0000
1.0
BT-20 SHP099
inf
 0.8790 0.0132 0.0000 0.9876 0.0100 0.0000
0.0930371400466
HCC1419 SHP099
inf
 0.7338 0.0420 0.0000 0.9489 0.0100 0.0000
0.203508371
MDA-MB-231 Senexin B
inf
 0.8570 0.0825 0.0000 0.9166 0.0100 0.0000
0.184944177707
HCC1954 Rucaparib
inf
 0.8492 0.0892 0.0000 0.9429 0.0100 0.0000
1.0