Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1500 P22077
31.6
 -0.4017 0.48425
HCC1500 P22077
50.0
 -0.4885 0.06460
HCC1500 PB49673382
0.009992797
 0.9484 0.01783
HCC1500 PB49673382
0.0316
 0.8894 -0.01315
HCC1500 PB49673382
0.099927974
 1.0092 -0.00387
HCC1500 PB49673382
0.316
 0.8868 0.00092
HCC1500 PB49673382
0.999279741
 0.7983 0.02022
HCC1500 PB49673382
3.16
 0.3193 0.16053
HCC1500 PB49673382
9.992797406
 -0.2915 0.47283
HCC1500 PB49673382
31.6
 -0.3642 0.47670
HCC1500 PB49673382
50.0
 -0.3620 0.50196
HCC1500 Pimozide
0.009992797
 0.9454 -0.00674
HCC1500 Pimozide
0.0316
 1.0230 -0.00131
HCC1500 Pimozide
0.099927974
 0.9304 0.00791
HCC1500 Pimozide
0.316
 0.7896 0.00513
HCC1500 Pimozide
0.999279741
 0.7738 0.00981
HCC1500 Pimozide
3.16
 0.8066 0.03723
HCC1500 Pimozide
9.992797406
 0.3708 0.14260
HCC1500 Pimozide
31.6
 -0.5563 0.54466
HCC1500 Pimozide
50.0
 -0.5492 0.52625
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.7826 -0.00580
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9071 0.02727
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.1016 0.02038
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0226 0.00349
HCC1500 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9882 0.00652