Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1500 | ML-323 | 0.009992797 | 0.9266 | -0.00592 |
| HCC1500 | ML-323 | 0.0316 | 0.9839 | -0.01308 |
| HCC1500 | ML-323 | 0.099927974 | 1.0029 | 0.01336 |
| HCC1500 | ML-323 | 0.316 | 1.2252 | 0.03905 |
| HCC1500 | ML-323 | 0.999279741 | 0.9601 | 0.01360 |
| HCC1500 | ML-323 | 3.16 | 0.6905 | 0.04850 |
| HCC1500 | ML-323 | 9.992797406 | 0.8218 | 0.02008 |
| HCC1500 | ML-323 | 31.6 | 0.4049 | 0.10055 |
| HCC1500 | ML-323 | 50.0 | 0.1643 | 0.23806 |
| HCC1500 | Pevonedistat | 0.009992797 | 0.9966 | 0.05230 |
| HCC1500 | Pevonedistat | 0.0316 | 0.8604 | 0.06348 |
| HCC1500 | Pevonedistat | 0.099927974 | 0.5687 | 0.11670 |
| HCC1500 | Pevonedistat | 0.316 | 0.3544 | 0.12435 |
| HCC1500 | Pevonedistat | 0.999279741 | 0.2411 | 0.15840 |
| HCC1500 | Pevonedistat | 3.16 | 0.2538 | 0.20271 |
| HCC1500 | Pevonedistat | 9.992797406 | 0.2644 | 0.23159 |
| HCC1500 | Pevonedistat | 31.6 | 0.2304 | 0.25469 |
| HCC1500 | Pevonedistat | 50.0 | 0.1450 | 0.09376 |
| HCC1500 | P22077 | 0.009992797 | 0.9622 | 0.00362 |
| HCC1500 | P22077 | 0.0316 | 0.8641 | 0.00219 |
| HCC1500 | P22077 | 0.099927974 | 1.0406 | 0.02053 |
| HCC1500 | P22077 | 0.316 | 0.9768 | -0.01744 |
| HCC1500 | P22077 | 0.999279741 | 1.0141 | -0.00428 |
| HCC1500 | P22077 | 3.16 | 0.8338 | 0.07464 |
| HCC1500 | P22077 | 9.992797406 | 0.4730 | 0.38701 |