Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MCF7 | HY-17541A | 9.992797406 | 0.5063 | 0.18111 |
| MCF7 | HY-17541A | 31.6 | -0.2310 | 0.41647 |
| MCF7 | HY-17541A | 50.0 | -0.3502 | 0.41596 |
| MCF7 | HY-17542 | 0.009992797 | 1.0004 | -0.00075 |
| MCF7 | HY-17542 | 0.0316 | 0.9628 | -0.00019 |
| MCF7 | HY-17542 | 0.099927974 | 1.0045 | -0.00260 |
| MCF7 | HY-17542 | 0.316 | 1.0359 | -0.00298 |
| MCF7 | HY-17542 | 0.999279741 | 0.9756 | -0.00087 |
| MCF7 | HY-17542 | 3.16 | 1.0051 | -0.00052 |
| MCF7 | HY-17542 | 9.992797406 | 1.0151 | -0.00212 |
| MCF7 | HY-17542 | 31.6 | 0.9501 | -0.00029 |
| MCF7 | HY-17542 | 50.0 | 0.9160 | 0.03076 |
| MCF7 | HY-50736 | 0.009992797 | 0.9353 | 0.00076 |
| MCF7 | HY-50736 | 0.0316 | 0.5765 | 0.01679 |
| MCF7 | HY-50736 | 0.099927974 | 0.2987 | 0.05686 |
| MCF7 | HY-50736 | 0.316 | -0.0937 | 0.25086 |
| MCF7 | HY-50736 | 0.999279741 | -0.2809 | 0.58291 |
| MCF7 | HY-50736 | 3.16 | -0.2663 | 0.59442 |
| MCF7 | HY-50736 | 9.992797406 | -0.1853 | 0.56925 |
| MCF7 | HY-50736 | 31.6 | -0.1348 | 0.49029 |
| MCF7 | HY-50736 | 50.0 | -0.1311 | 0.48981 |
| MCF7 | HY-50737A | 0.009992797 | 1.0114 | -0.00155 |
| MCF7 | HY-50737A | 0.0316 | 0.9971 | 0.00079 |
| MCF7 | HY-50737A | 0.099927974 | 0.7515 | 0.00810 |
| MCF7 | HY-50737A | 0.316 | 0.3474 | 0.03845 |