Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MCF 10A | IU1 | 50.0 | 0.9050 | 0.00170 |
| MCF 10A | LDN57444 | 0.009992797 | 0.9986 | 0.00109 |
| MCF 10A | LDN57444 | 0.0316 | 0.9634 | -0.00085 |
| MCF 10A | LDN57444 | 0.099927974 | 1.0044 | 0.00130 |
| MCF 10A | LDN57444 | 0.316 | 0.9571 | 0.00017 |
| MCF 10A | LDN57444 | 0.999279741 | 0.9973 | 0.00144 |
| MCF 10A | LDN57444 | 3.16 | 0.9794 | 0.00489 |
| MCF 10A | LDN57444 | 9.992797406 | 0.8458 | 0.02518 |
| MCF 10A | LDN57444 | 31.6 | 0.4130 | 0.24614 |
| MCF 10A | LDN57444 | 50.0 | -0.1381 | 0.30954 |
| MCF 10A | MI-2 | 0.009992797 | 1.0083 | 0.00083 |
| MCF 10A | MI-2 | 0.0316 | 1.0057 | -0.00067 |
| MCF 10A | MI-2 | 0.099927974 | 0.9957 | -0.00131 |
| MCF 10A | MI-2 | 0.316 | 1.0052 | 0.00047 |
| MCF 10A | MI-2 | 0.999279741 | 0.9784 | 0.00205 |
| MCF 10A | MI-2 | 3.16 | 0.9261 | 0.13042 |
| MCF 10A | MI-2 | 9.992797406 | -0.0627 | 0.43217 |
| MCF 10A | MI-2 | 31.6 | -0.2193 | 0.61932 |
| MCF 10A | MI-2 | 50.0 | -0.2953 | 0.45146 |
| MCF 10A | Mitoxantrone | 0.009992797 | 0.7099 | 0.05613 |
| MCF 10A | Mitoxantrone | 0.0316 | 0.2866 | 0.14198 |
| MCF 10A | Mitoxantrone | 0.099927974 | 0.0670 | 0.16340 |
| MCF 10A | Mitoxantrone | 0.316 | 0.0088 | 0.12887 |
| MCF 10A | Mitoxantrone | 0.999279741 | -0.0065 | 0.43237 |
| MCF 10A | Mitoxantrone | 3.16 | -0.1652 | 0.65160 |