Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
HCC38 Taxol
Chemo
Chemotherapy
0.0014659
 -0.3078 0.8432 0.2758 2.3201
0.0017274
0.99328
CAL-120 Taxol
Chemo
Chemotherapy
0.0028769
 -0.1987 0.7463 0.3104 2.6390
0.0032354
0.97877
BT-549 Taxol
Chemo
Chemotherapy
0.0027257
 -0.2074 0.6989 0.2304 1.9420
0.0030953
0.98743
HCC1143 Taxol
Chemo
Chemotherapy
0.0020688
 -0.3349 0.8388 0.3074 2.5955
0.0024565
0.99279
BT-20 Taxol
Chemo
Chemotherapy
0.0020158
 -0.5760 0.9854 0.4456 2.0677
0.0028795
0.99355
PDXHCI002 Taxol
Chemo
Chemotherapy
0.0024935
 -0.5117 0.9207 0.3881 2.7479
0.0031656
0.99139
SK-BR-3 Taxol
Chemo
Chemotherapy
0.0019068
 -0.3401 0.8905 0.3665 2.3888
0.0023578
0.96349
SUM149PT Taxol
Chemo
Chemotherapy
0.0015927
 -0.2583 0.8405 0.3816 3.1045
0.0017914
0.99574
T47D Taxol
Chemo
Chemotherapy
0.0035285
 -0.1337 0.6636 0.2505 2.2353
0.0038792
0.99665
MDA-MB-231 Taxol
Chemo
Chemotherapy
0.0023185
 -0.1204 0.7021 0.2576 1.1720
0.0026636
0.96432
CAMA-1 Taxol
Chemo
Chemotherapy
0.0022699
 -0.4944 0.9525 0.3547 2.4920
0.0029769
0.99478
HCC1806 Taxol
Chemo
Chemotherapy
0.0014225
 -0.2113 0.8398 0.3493 2.1569
0.0016621
0.96243
MCF7 Taxol
Chemo
Chemotherapy
0.0013771
 -0.1059 0.7722 0.1589 1.1560
0.0016261
0.94939
HCC1428 Taxol
Chemo
Chemotherapy
0.0086248
 0.0645 0.5066 0.2045 0.7260
0.0074214
0.91451
MCF 10A Taxol
Chemo
Chemotherapy
0.0026843
 -0.1256 0.7023 0.2576 1.8234
0.003018
0.9967
HME1 Taxol
Chemo
Chemotherapy
0.0031675
 -0.2241 0.6794 0.2401 1.5314
0.0037399
0.98563
SUM1315MO2 Taxol
Chemo
Chemotherapy
0.0024623
 -0.3258 0.7931 0.2940 2.0093
0.0030737
0.99498
Hs 578T Taxol
Chemo
Chemotherapy
0.0010154
 -0.3752 0.9535 0.4788 1.2811
0.0015458
0.95438
SUM159PT Taxol
Chemo
Chemotherapy
0.0047473
 -0.1485 0.6380 0.2976 2.2238
0.0052544
0.99906
MDA-MB-436 Taxol
Chemo
Chemotherapy
0.0037097
 -0.2183 0.7083 0.1530 3.2043
0.0040962
0.99739
HCC38 TGX221
PI3Kb
PI3K/mTOR
Inf
 0.9515 -0.0246 0.0013 0.0000
Inf
-0.17011
Hs 578T TGX221
PI3Kb
PI3K/mTOR
34.4921
 0.7094 0.0668 0.0103 0.5623
243.351
0.9333
SUM159PT TGX221
PI3Kb
PI3K/mTOR
Inf
 0.9906 -0.0088 -0.0001 0.0000
Inf
-0.54094
CAMA-1 TGX221
PI3Kb
PI3K/mTOR
42.7345
 0.8500 0.0067 0.0034 0.9968
118.889
0.79474
BT-549 TGX221
PI3Kb
PI3K/mTOR
Inf
 0.8097 0.0568 0.0017 0.6702
0.72927
0.89208