Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-20 Luminespib
0.01
HSP90
Misc
 0.0615 0.20799
BT-20 Luminespib
0.031623
HSP90
Misc
 -0.0133 0.25929
BT-20 Luminespib
0.1
HSP90
Misc
 -0.0431 0.27116
BT-20 Luminespib
0.31623
HSP90
Misc
 -0.0490 0.26468
BT-20 Luminespib
1.0
HSP90
Misc
 -0.0477 0.29666
BT-20 A-1210477
0.001
Mcl-1
Misc
 1.0130 -0.01627
BT-20 A-1210477
0.0031623
Mcl-1
Misc
 0.9994 -0.00302
BT-20 A-1210477
0.01
Mcl-1
Misc
 1.0461 0.00227
BT-20 A-1210477
0.031623
Mcl-1
Misc
 1.0678 -0.00128
BT-20 A-1210477
0.1
Mcl-1
Misc
 1.0869 -0.00182
BT-20 A-1210477
0.31623
Mcl-1
Misc
 1.0544 -0.00191
BT-20 A-1210477
1.0
Mcl-1
Misc
 1.0474 -0.00138
BT-20 A-1210477
3.1623
Mcl-1
Misc
 1.0977 -0.01661
BT-20 A-1210477
10.0
Mcl-1
Misc
 0.8209 0.04589
BT-20 Olaparib
0.001
PARP
Misc
 1.0265 -0.00519
BT-20 Olaparib
0.0031623
PARP
Misc
 1.0048 0.00222
BT-20 Olaparib
0.01
PARP
Misc
 0.9547 0.00738
BT-20 Olaparib
0.031623
PARP
Misc
 1.0085 0.00586
BT-20 Olaparib
0.1
PARP
Misc
 0.9632 0.00208
BT-20 Olaparib
0.31623
PARP
Misc
 0.9400 0.00840
BT-20 Olaparib
1.0
PARP
Misc
 0.9125 0.00565
BT-20 Olaparib
3.1623
PARP
Misc
 0.8745 0.00918
BT-20 Olaparib
10.0
PARP
Misc
 0.6064 0.04246
BT-20 Bleomycin
0.0010833
Radiation
Misc
 0.9824 0.00530
BT-20 Bleomycin
0.0033333
Radiation
Misc
 0.9945 0.00019