Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MDA-MB-231 A-1210477
3.1623
Mcl-1
Misc
 0.9775 0.00062
MDA-MB-231 A-1210477
10.0
Mcl-1
Misc
 0.9569 0.00505
MDA-MB-231 Olaparib
0.001
PARP
Misc
 0.9799 -0.00024
MDA-MB-231 Olaparib
0.0031623
PARP
Misc
 0.9888 0.00197
MDA-MB-231 Olaparib
0.01
PARP
Misc
 1.0059 0.00169
MDA-MB-231 Olaparib
0.031623
PARP
Misc
 0.9648 0.00138
MDA-MB-231 Olaparib
0.1
PARP
Misc
 1.0043 -0.00248
MDA-MB-231 Olaparib
0.31623
PARP
Misc
 0.9668 0.00106
MDA-MB-231 Olaparib
1.0
PARP
Misc
 0.9368 -0.00682
MDA-MB-231 Olaparib
3.1623
PARP
Misc
 0.8689 0.01080
MDA-MB-231 Olaparib
10.0
PARP
Misc
 0.6179 0.03791
MDA-MB-231 Bleomycin
0.0010833
Radiation
Misc
 0.9621 -0.00198
MDA-MB-231 Bleomycin
0.0033333
Radiation
Misc
 0.9536 0.00041
MDA-MB-231 Bleomycin
0.01
Radiation
Misc
 0.9698 -0.00109
MDA-MB-231 Bleomycin
0.031667
Radiation
Misc
 0.9672 -0.00101
MDA-MB-231 Bleomycin
0.1
Radiation
Misc
 0.9475 -0.00064
MDA-MB-231 Bleomycin
0.31623
Radiation
Misc
 0.9526 -0.00281
MDA-MB-231 Bleomycin
1.0
Radiation
Misc
 0.8464 -0.00112
MDA-MB-231 Bleomycin
3.1623
Radiation
Misc
 0.6142 0.00839
MDA-MB-231 Bleomycin
10.0
Radiation
Misc
 0.4365 0.02704
MDA-MB-231 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9731 0.00287
MDA-MB-231 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9806 0.00474
MDA-MB-231 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0561 0.00541
MDA-MB-231 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0315 -0.00166
MDA-MB-231 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9871 -0.00637