Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Bleomycin
10.0
Radiation
Misc
 -0.0365 0.20034
CAMA-1 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9540 -0.00406
CAMA-1 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9500 -0.00273
CAMA-1 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0456 -0.00906
CAMA-1 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8955 -0.00218
CAMA-1 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7817 0.00048
CAMA-1 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.4440 0.02939
CAMA-1 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.2447 0.08663
CAMA-1 Ipatasertib
3.1623
AKT
PI3K/mTOR
 -0.0131 0.22616
CAMA-1 Ipatasertib
10.0
AKT
PI3K/mTOR
 -0.2361 0.42872
CAMA-1 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9251 0.00764
CAMA-1 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.8864 0.00676
CAMA-1 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 1.0178 0.00209
CAMA-1 Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.9748 0.00282
CAMA-1 Alpelisib
0.1
PI3Ka
PI3K/mTOR
 1.0185 0.00312
CAMA-1 Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 1.0281 0.00074
CAMA-1 Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.9959 0.00405
CAMA-1 Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 1.0419 0.00522
CAMA-1 Alpelisib
10.0
PI3Ka
PI3K/mTOR
 0.9788 0.01765
CAMA-1 Taselisib
0.001
PI3Ka, g, d
PI3K/mTOR
 0.9878 0.00563
CAMA-1 Taselisib
0.0031623
PI3Ka, g, d
PI3K/mTOR
 0.9302 0.00843
CAMA-1 Taselisib
0.01
PI3Ka, g, d
PI3K/mTOR
 1.0142 0.00069
CAMA-1 Taselisib
0.031623
PI3Ka, g, d
PI3K/mTOR
 0.8958 0.00209
CAMA-1 Taselisib
0.1
PI3Ka, g, d
PI3K/mTOR
 0.9834 0.00562
CAMA-1 Taselisib
0.31623
PI3Ka, g, d
PI3K/mTOR
 0.8057 0.01324