Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
T47D | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.7136 | 0.00756 |
T47D | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.2284 | 0.01447 |
T47D | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.1019 | 0.03321 |
T47D | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.8837 | 0.00193 |
T47D | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.7842 | 0.00725 |
T47D | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.2335 | 0.02430 |
T47D | Doxorubicin | 0.01 | Chemo | Chemotherapy | -0.0015 | 0.03141 |
T47D | Doxorubicin | 0.031623 | Chemo | Chemotherapy | -0.0535 | 0.04115 |
T47D | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.1199 | 0.11043 |
T47D | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.1794 | 0.15710 |
T47D | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.3611 | 0.36359 |
T47D | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.1901 | 0.17524 |
T47D | Taxol | 0.0001 | Chemo | Chemotherapy | 0.9933 | 0.01216 |
T47D | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0719 | -0.00300 |
T47D | Taxol | 0.001 | Chemo | Chemotherapy | 0.9767 | 0.02721 |
T47D | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.5550 | 0.24030 |
T47D | Taxol | 0.01 | Chemo | Chemotherapy | 0.0121 | 0.42909 |
T47D | Taxol | 0.031623 | Chemo | Chemotherapy | -0.0654 | 0.42448 |
T47D | Taxol | 0.1 | Chemo | Chemotherapy | -0.1580 | 0.34971 |
T47D | Taxol | 0.31623 | Chemo | Chemotherapy | -0.1092 | 0.36416 |
T47D | Taxol | 1.0 | Chemo | Chemotherapy | -0.1337 | 0.41010 |
T47D | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.8845 | -0.00136 |
T47D | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.6899 | 0.00417 |
T47D | Topotecan | 0.01 | Topo I | Chemotherapy | 0.2152 | 0.03522 |
T47D | Topotecan | 0.031667 | Topo I | Chemotherapy | -0.0553 | 0.08658 |