Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
PDXHCI002 Luminespib
0.0031623
HSP90
Misc
 0.7921 0.03246
PDXHCI002 Luminespib
0.01
HSP90
Misc
 -0.1757 0.24976
PDXHCI002 Luminespib
0.031623
HSP90
Misc
 -0.2577 0.26266
PDXHCI002 Luminespib
0.1
HSP90
Misc
 -0.2563 0.27236
PDXHCI002 Luminespib
0.31623
HSP90
Misc
 -0.2662 0.27782
PDXHCI002 Luminespib
1.0
HSP90
Misc
 -0.2805 0.27430
PDXHCI002 A-1210477
0.001
Mcl-1
Misc
 1.0140 0.00331
PDXHCI002 A-1210477
0.0031623
Mcl-1
Misc
 1.0261 0.00136
PDXHCI002 A-1210477
0.01
Mcl-1
Misc
 1.1053 0.00313
PDXHCI002 A-1210477
0.031623
Mcl-1
Misc
 1.0562 0.00614
PDXHCI002 A-1210477
0.1
Mcl-1
Misc
 1.0709 0.00182
PDXHCI002 A-1210477
0.31623
Mcl-1
Misc
 1.0375 0.00572
PDXHCI002 A-1210477
1.0
Mcl-1
Misc
 1.0639 0.00479
PDXHCI002 A-1210477
3.1623
Mcl-1
Misc
 1.0427 0.00701
PDXHCI002 A-1210477
10.0
Mcl-1
Misc
 0.9814 0.01081
PDXHCI002 Olaparib
0.001
PARP
Misc
 1.0675 -0.00603
PDXHCI002 Olaparib
0.0031623
PARP
Misc
 1.0165 -0.01257
PDXHCI002 Olaparib
0.01
PARP
Misc
 0.9830 -0.01030
PDXHCI002 Olaparib
0.031623
PARP
Misc
 0.9559 -0.00857
PDXHCI002 Olaparib
0.1
PARP
Misc
 0.9174 -0.00183
PDXHCI002 Olaparib
0.31623
PARP
Misc
 0.8214 0.00171
PDXHCI002 Olaparib
1.0
PARP
Misc
 0.7341 0.01451
PDXHCI002 Olaparib
3.1623
PARP
Misc
 0.5714 0.04279
PDXHCI002 Olaparib
10.0
PARP
Misc
 0.2648 0.13590
PDXHCI002 Bleomycin
0.0010833
Radiation
Misc
 0.8970 0.00663