Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Bleomycin
3.1623
Radiation
Misc
 -0.0733 0.48652
Hs 578T Bleomycin
10.0
Radiation
Misc
 -0.1966 0.56324
Hs 578T Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9300 0.00230
Hs 578T Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9722 -0.00367
Hs 578T Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9359 0.00166
Hs 578T Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8534 -0.00386
Hs 578T Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7471 0.00023
Hs 578T Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.6874 0.00323
Hs 578T Ipatasertib
1.0
AKT
PI3K/mTOR
 0.5990 0.01091
Hs 578T Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.5525 0.03059
Hs 578T Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4423 0.04240
Hs 578T Alpelisib
0.001
PI3Ka
PI3K/mTOR
 1.0185 0.00314
Hs 578T Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9626 0.00354
Hs 578T Alpelisib
0.01
PI3Ka
PI3K/mTOR
 0.9950 0.00318
Hs 578T Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.9691 0.00079
Hs 578T Alpelisib
0.1
PI3Ka
PI3K/mTOR
 0.9449 -0.00022
Hs 578T Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 0.9224 0.00125
Hs 578T Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.9027 0.00200
Hs 578T Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 0.8050 0.00474
Hs 578T Alpelisib
10.0
PI3Ka
PI3K/mTOR
 0.5308 0.03847
Hs 578T Taselisib
0.001
PI3Ka, g, d
PI3K/mTOR
 0.9919 -0.00406
Hs 578T Taselisib
0.0031623
PI3Ka, g, d
PI3K/mTOR
 0.9590 0.00254
Hs 578T Taselisib
0.01
PI3Ka, g, d
PI3K/mTOR
 0.8643 0.00072
Hs 578T Taselisib
0.031623
PI3Ka, g, d
PI3K/mTOR
 0.7712 0.03174
Hs 578T Taselisib
0.1
PI3Ka, g, d
PI3K/mTOR
 0.6676 0.02504